2008 Rustbelt RNA Meeting






Friday, Oct 17
12:00-01:00pmMeeting Registration (Foyer)
01:00-01:10pmOpening Remarks (Organizers, Dawn Chandler and Girish Shukla and Founder, Dan Schoenberg)
Session I: Translation Control & Stability (Dawn Chandler)
01:10-01:30pmTitle not published online - please see printed booklet
Abul Arif, Paul L. Fox
Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195
01:30-01:50pmGenome wide screening for target mRNAs silenced translationally upon IFN-gamma treatment
Keyur Vyas, Sujan Chaudhuri, Anton A. Komar,, Douglas Leaman, Alla Musiyenko, Sailen Barik, Barsanjit Mazumder
Center for Gene Regulation in Health and Disease, BGES, Cleveland State Univ., OH
01:50-02:10pmThe Ena/VASP proteins are unanticipated partners of the PMR1 mRNA endonuclease that may function to localize mRNA decay
Yong Peng, Xiaoqiang Liu, Elizabeth Murray, Madhubanti Sarkar, Daniel Schoenberg
Department of Molecular and Cellular Biochemistry, OSU
02:10-02:30pmEukaryotic mRNA decay occurs on polyribosomes
Wenqian Hu, Thomas Sweet, Kristian E. Baker, Jeff Coller
Center for RNA Molecular Biology, Case Western Reserve University
02:30-02:50pmInvestigating the role for the 3’ UTR in nonsense-mediated mRNA decay
Edward M. Turk, Caitlin Finelli, Kristian E. Baker
Center for RNA Molecular Biology, CWRU
02:50-03:10pmCoffee Break
Session II: Regulation & RNA Processing (Andrea Ladd)
03:10-03:30pmInduction of neuronal differentiation in muscle precursor cells by a large non-coding RNA
Bing Zhang, Fereshteh Jahaniani Kenari
Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, OH 44106, USA
03:30-03:50pmInterdependence of poly(A) polymerase and helicase activities in the TRAMP complex
Huijue Jia, Xuying Wang, Fei Liu, James T. Anderson, Eckhard Jankowsky
Department of Biochemistry, Center for RNA Molecular Biology, Case Western Reserve University
03:50-04:10pmDEAD-box proteins utilize different displacement approaches for RNA duplexes unwinding.
Ivelitza Garcia, Olke C. Uhlenbeck
Chemistry Department, Allegheny College
04:10-04:30pmSingle molecule observations of pre-mRNA dynamics during splicing
Mario R. Blanco, Mark Ditzler, Frank Fuller, Mona Wood, John Abelson, Nils Walter
Cellular and Molecular Biology, University of Michigan
04:30-04:50pmThe ability to catalyze protein-free splicing is phylogenetically conserved from yeast to human
Caroline Lee, Saba Valadkhan
Biochemistry, Case Western Reserve University
04:50-05:10pmBreak and short PI organizational meeting
Session III: RNA and human disease (Saba Valadkhan)
05:10-05:30pmMouse Smn Exon 7 C>T: A Smn2 like Knock-in Mouse Model of Spinal Muscular Atrophy
Jordan T. Gladman, Thomas W. Bebee, Dawn S. Chandler
The Center for Childhood Cancer, Columbus Children’s Research Institute, The Department of Pediatrics, The Ohio State University.
05:30-05:50pmThe use of peptides for novel antibiotic development against the bacterial ribosome
Anne-Cecile E. Duc, Mei Li, Christine S. Chow
Department of Chemistry, Wayne State University
05:50-06:10pmInositol phosphate-mediated switch in the nucleic acid chaperone activity of HIV-1 Gag
Christopher P. Jones, Siddhartha A. K. Datta, Alan Rein, Karin Musier-Forsyth
Chemistry and Biochemistry, The Ohio State University
06:10-06:30pmMicroRNAs in the NF-kappaB Pathway
Zhongxin Lu, Apana Takwi, Yanglong Zhu, Yong Li
Department of Biochemistry and Molecular Biology
06:30-07:30pmDinner (Upstairs in the Mezzanine)
Session IV: Poster Session - Scarlet Oak Room
07:30-09:00pmOdd posters present
09:00-10:30pmEven Posters present
10:30-12:00amEvening Reception (Central Lobby Area)
11:30-12:00amPlease remove posters by midnight
Saturday, Oct 18
07:00-08:00amContinental Breakfast (Rafter's Restaurant with Coupon)
Session V: Structure (Jane Jackman)
08:00-08:20amHeat Shock and Post-transcriptional Modifications in bacterial ribosomal RNA
Susan Russell, Dr. Patrick Limbach
University of Cincinnati
08:20-08:40amGenetic identification of 16S rRNA residues required for accurate start codon selection
Daoming Qin, Kurt Fredrick
The Ohio State Biochemistry Program
08:40-09:00amNMR studies of protein interactions in archaeal RNase P
Yiren Xu, Carlos D. Amero, William P. Boomershine, Mark P. Foster
OSU Biochemistry
09:00-09:20amA catalytic metal ion interacts with the cleavage site G•U wobble in the HDV ribozyme
Jui-Hui Chen, Bo Gong, Philip C. Bevilacqua, Paul R. Carey, Barbara L. Golden
Department of Biochemistry, Purdue University, 175 South University Street, West Lafayette, Indiana 47907
09:20-09:40amA conformational change regulates cleavage to generate the 3’ end of 18S rRNA in yeast
Allison C. Lamanna, Katrin Karbstein
Department of Chemistry, University of Michigan
09:40-10:00amLaser-Assisted Single Molecule Refolding
Rui Zhao, Elvin A. Alem225n, Rajan Lamichhane, David Rueda
Chemistry, Wayne State University
10:00-10:20amCoffee Break
Session VI: RNA Complex Interactions & Bioinformatics (Girish Shukla)
10:20-10:40ampRNA and DNA-dependent ATPase activity of gp16 of bacterial virus phi29 DNA packaging motor
Tae Jin Lee, Hui Zhang, Dan Liang, Peixuan Guo
Biomedical Engineering, University of Cincinnati
10:40-11:00amRetrovirus-Specific Differences in Protein-Nucleic Acid Interactions: Implications for Genomic RNA Packaging
Meng Sun, Robert J. Gorelick, Louis M. Mansky, Karin Musier-Forsyth
Departments of Chemistry, The Ohio State University, Columbus, OH 43210
11:00-11:20amNovel mechanism of hexamer assembly in protein/RNA interactions revealed by single molecule imaging.
Feng Xiao, Hui Zhang, Peixuan Guo
Biomedical Engineering, University of Cincinnati
11:20-11:40amRNA Paranemic-Binding Motifs for Biosensing and Nano-assembly
Irina Novikova, Kirill A. Afonin, Evgeny O. Danilov, Neocles B. Leontis
Chemistry, Bowling Green State University
11:40-11:55amhnRNPH is required for optimal binding of U1 snRNP and helps recruit hnRNPF to a complex array of G runs that regulate PLP/DM20 rati
Erming Wang, Giulio Disanto, Franca Cambi
Neurology, University of Kentucky
11:55-12:10pmVisualizing non-consensus interpositional requirements in nucleic-acid families
William Ray
The Research Institute at Nationwide Childrens Hospital
12:10-12:25pmGene hunting with forests for multigroup time course data
Ariadni Papana, Hemant Ishwaran
Department of Mathematics, Cleveland State University
12:25-12:40pmClosing remarks and presentation of awards (2009 Organizer, Girish Shukla & 2009 Co-organizer, to be named)