2013 Rustbelt RNA Meeting







Friday, Oct 18
11:00-01:00pmRegistration and Poster set-up (odd numbered posters)
Session I: Ribosome Assembly and Mechanisms of Translational Control
12:45-01:00pmWelcome and Opening remarks
01:00-01:15pmTitle not published online - please see printed booklet
Sandeepa M. Eswarappa, Alka Potdar, William Koch , Paul L. Fox
Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute
01:15-01:30pmDistinct functional classes of ribosomal ambiguity (ram) mutations in 16S rRNA
Sean P. McClory, Aishwarya Devaraj, Kurt Fredrick
Ohio State University, Dept. of Microbiology, Center for RNA Biology
01:30-01:45pmActively translating deadenylated mRNAs in D. melanogaster S2 cells
Trinh T. Tat, Patricia Maroney, Timothy W. Nilsen
Center for RNA Molecular Biology-Department of Biochemistry
01:45-02:00pmHIV-1 requires two non-redundant functions of host RNA helicase A: helicase activity for mRNA translation and chaperone activity for virion replication
Ioana Boeras, Kathleen Boris-Lawrie
Department of Veterinary Biosciences, Center for Retrovirus Research, Center for RNA Biology, Ohio State University, Columbus Ohio, USA
02:00-02:15pmA hierarchical view of the eukaryotic large ribosomal subunit assembly line
Michael Gamalinda, Uli Ohmayer, Jelena Jakovljevic, Beril Kumcuoglu, Joshua Woolford, Betty Mbom, Lawrence Lin, John L. Woolford, Jr.
Dept. of Biological Sciences, Carnegie Mellon University
02:15-02:30pmImp3 unfolds stem structures in pre-rRNA and U3 snoRNA to form a duplex essential for small subunit processing
Xin Liu, Binal N. Shah, Carl C. Correll
Department of BMB, Rosalind Franklin University
02:30-02:45pmA tRNA m3C methyltransferase paralog is important for ribosome biogenesis and cell division in T. brucei
Ian M.C. Fleming, Zdenek Paris, Mary Anne T. Rubio, Paul J. Sample, Juan D. Alfonzo
Department of Microbiology and The Center for RNA Biology, The Ohio State University
02:45-03:15pmCoffee Break
Session II: RNA Processing and Turnover
03:15-03:30pmSF2/ASF Modulates Alternative Splicing of MDM2 in Cancer
Daniel F. Comiskey Jr., Aishwarya G. Jacob, Ravi K. Singh, Aixa S. Tapia-Santos, Dawn S. Chandler
Department of Pediatrics, The Ohio State University
03:30-03:45pmPhenotypic analysis of a mouse model of human MOPD I
Faegheh Jafarifar, David E. Symer, Richard A. Padgett
Molecular Genetics, Cleveland Clinic, Lerner Research Institute
03:45-04:00pmCalcium-mediated epigenetic regulation of alternative splicing in cardiomyocytes
Alok Sharma, Hua Lou
Department of Genetics and Genome Sciences
04:00-04:15pmSMG6 cleavage generates metastable decay intermediates from nonsense-containing β-globin mRNA
Julie A. Dougherty, Roshan Mascarenhas, Daniel R. Schoenberg
Molecular & Cellular Biochemistry, Ohio State University
04:15-04:30pmTitle not published online - please see printed booklet
Jenna Smith, Sarah Geisler, Juan Alvarez, Jeff Coller, Kristian Baker
Center for RNA Molecular Biology, Case Western Reserve University
04:30-04:45pmTitle not published online - please see printed booklet
Nathan Raynard, Joel Hrit, Adam Petterson, Aaron Goldstrohm
Department of Biological Chemistry and Genetics Training Program, University of Michigan
04:45-05:00pmPoly (A) binding protein C1 is developmentally regulated and controls a post-transcriptional pathway for cardiac hypertrophy.
Sandip Chorghade, Auinash kalsotra, Michael De Lisio
Biochemestry, University of Illinois, Urbana-Champaign
05:00-05:20pmPI meeting and additional time for Poster set-up
05:20-06:30pmKeynote Lecture, Dr Tom Cech, University of Colorado Boulder and HHMI
Saturday, Oct 19
06:30-08:30amBreakfast- David's Restaurant, Marriott Lobby Level
Session III: RNA and RNP Structure and Engineering
08:30-08:45amSAXS-derived structure of HIV-1 genome 5´UTR reveals independently folded functional domains and three-dimensional tRNA mimicry
William A. Cantara, Christopher P. Jones, Erik D. Olson, William C. Ho, Steve Tuske, Eddy Arnold, Karin Musier-Forsyth
Department of Chemistry and Biochemistry, Center for Retrovirus Research, and Center for RNA Biology, The Ohio State University, Columbus OH 43210
08:45-09:00amEvolution of Ancestral URB Protein Toward Modern U1A/U2´´ snRNP proteins.
Kimberly J. Delaney, Sandra G. Williams, Mariah Lawler, Kathleen B. Hall
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine
09:00-09:15amMod-seq: High-throughput sequencing for chemical probing of RNA structure
Jason Talkish, Gemma E. May, John L. Woolford, Jr., C. Joel McManus
Biological Sciences, Carnegie Mellon University
09:15-09:30amKinetics and Thermodynamics of the Juctionless Hairpin Ribozyme
Neil A. White, Charles G. Hoogstraten
Biochemistry and Molecular Biology, Michigan State University
09:30-09:45amDivision of labor: Separation of loading and unwinding units in an oligomer of the DEAD-box helicase Ded1p
Andrea Putnam, Huijue Jia, Fei Liu, Quansheng Yang, Eckhard Jankowsky
09:45-10:00am Modulation of gene expression by inducing G-quadruplex structures in the 5'-UTR
Debmalya Bhattacharyya, Kim Nguyen, Soumitra Basu
Chemistry and Biochemistry, Kent State University
10:00-10:15amThree Approaches for Construction of Versatile RNA Nanoparticles for Specific Tumor Targeting
Yi Shu, Farzin Haque, Dan Shu, Wei Li, Peixuan Guo
Nanobiotechnology Center, Markey Cancer Center, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky
10:15-10:45amCoffee Break
Session IV: RNA-Mediated Regulation of Gene Expression
10:45-11:00amLipid II-independent trans Editing of Mischarged tRNAs by the Penicillin Resistance Factor MurM
Jennifer Shepherd, Michael Ibba
Microbiology, The Ohio State University
11:00-11:15amThe bacterial-type tRNA-independent transamidosome complex requires a novel ATPase
Gayathri N. Silva, Tamara L. Hendrickson
Wayne State University
11:15-11:30ameIF4H alternative splicing is regulated by the microprocessor
Mallory A. Havens, Ashley A. Reich, Michelle L. Hastings
Department of Cell Biology and Anatomy, Rosalind Franklin University
11:30-11:45amThe Role of the Catalytically Inactive Deaminase ADR-1 in Regulating RNA Editing
Michael Washburn, Boyko Kakaradov, Gene Yeo, Heather Hundley
Department of Biology, Indiana University
11:45-12:00pmInvestigation of Shared Molecular Recognition of Pre-tRNAs By RNA and Protein Components of RNase P Using High-Throughput Sequencing Kinetics (HTS-Kin)
Courtney N. Niland, Ulf-Peter Guenter, Eckhard Jankowsky, Michael E. Harris
Department of Biochemistry, Case Western Reserve University
12:00-12:20pmIdentification of Neuronal Transcripts Regulated by a Nuclear Polyadenosine RNA Binding Protein
Seth M. Kelly, Andreas Kuss, Anita H. Corbett, Kenneth H. Moberg
Department of Biology, College of Wooster, Wooster, OH
12:20-12:40pmMolecular recognition of the SRA epigenetic regulatory lncRNA examined by NMR.
Thomas Leeper, Joel Caporoso, Daniel Morris, Caroline Davis, Stephanie Bilinovich
University of Akron
12:40-01:00pmClosing remarks and awards