Agenda

Log in and return to this page to see the full titles and abstracts.

Friday, Oct 18

TimeEvent
09:00-12:30pmOptional Workshops 1 and 2 (registration required)
01:00-01:15pmWelcome and Introductory remarks
  

Session I: Session 1: RNA Structure, Function & Dynamics

01:15-01:30pmKinetic modeling of chemical probing data enables extraction of intrinsic nucleotide energetics
Edric K. Choi, Ritwika Bose, Anthony M. Mustoe, Julius B. Lucks
Chemical and Biological Engineering, Northwestern University
01:30-01:45pmIdentification of leader-trailer helices of precursor ribosomal RNA in all phyla of bacteria and archaea
Bryan T. Gemler, Benjamin R. Warner, Ralf Bundschuh, Kurt Fredrick
Interdisciplinary Biophysics Graduate Program, The Ohio State University
01:45-02:00pmHow are RNA helicases recruited to their RNA substrates?
Taylor N. Ayers, Fiona Fitzgerald, Collin Bachert, John L. Woolford
Carnegie Mellon University
02:00-02:15pmSolution scattering as a structural tool for RNA and RNA:RNA complexes
Aldrex Munsayac, Wellington C. Leite, Jesse B. Hopkins, Ian Hall, Hugh M. ONeill, Sarah C. Keane
Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA
02:15-02:30pmSubstrate Recognition by Two 3' to 5' RNA Polymerases in Dictyostelium discoideum
Grace Johnecheck, Yicheng Long, Jane Jackman
Department of Chemistry and Biochemistry, Center for RNA Biology, and OSBP, The Ohio State University
02:30-02:45pmChanges in the non-coding RNAs of Glucose-Challenged Human Glomerular Epithelial Cells May Give Insights into the Progression of Diabetic Kidney Disease
Nik Tsotakos, Ryan Castaneira, Daniel Morris
Dept. of Biological Sciences, Penn State Harrisburg
02:45-03:15pmPI Meeting
02:45-03:15pmCoffee break
  

Session II: Session 2: RNA regulation

03:15-03:30pmRepression of Ago1 by Ago2 via let-7 microRNAs facilitates embryonic stem cell differentiation
Gabrielle M. Schuh, Katharine R. Maschhoff, Annastasia Minor, Wenqian Hu
Biochemistry and molecular biology, Mayo Clinic
03:30-03:45pmSubstrate Selection and Functional Outcomes by the mRNA modifying enzyme PUS7
Kira Holton, Brittany Bowman, Kristin Koutmou, Chase Weidmann
Department of Biological Chemistry, University of Michigan
03:45-04:00pmRNase H1 phosphorylation promotes RPA interaction to safeguard genome integrity from R-loop-associated instability
Victor M. Corral, Wannasiri Chiraphapphaiboon, Niraja A. Soman, Hai Dang Nguyen
Molecular Pharmacology and Therapeutics Graduate Program, Department of Pharmacology, University of Minnesota, Minneapolis MN
04:00-04:15pmPUMILIO post-transcriptional regulation of nuclear encoded mitochondrial genes in human cells.
Misbah Khan, Ronghao Chen, Swetha Rajasakaran, Jalal Siddiqui, Ganesh Koshre,Rebecca Lisi, Wayne Miles
The Ohio State University
04:15-04:30pmRibosomal release factors Hbs1 and Pelota regulate translation of coding regions following upstream open reading frames
Katherine Querry, Narayanan Nampoothiri, Chris Garbark, Nina Gralewski-Goel, Abigail Carney, Mykola Roiuk, Aurelio Teleman, Deepika Vasudevan
Department of Cell Biology, University of Pittsburgh School of Medicine
04:30-04:45pmTranslation of human papillomavirus E6 protein from mRNAs with extremely short 5′-UTRs
Ritam Neupane, Wenzhao Dong, Andrew Shurer, Jay B. Querido, Rachel O. Niederer
Department of Biological Chemistry, University of Michigan
04:45-04:45pmBrief Break
  
05:00-06:00pmKeynote lecture: Understanding RNA folding in vivo by two complementary approaches
Philip C. Bevilacqua, McCauley Meyer, Saehyun Choi, Christine D. Keating, Jacob P. Sieg, Sarah M. Assmann, Ryota Yamagami
Departments of Chemistry and of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, Penn State University
06:00-08:00pmDinner
08:00-11:00pmPoster Session and Reception

Saturday, Oct 19

TimeEvent
07:00-08:30amBreakfast
  

Session III: Session 3: RNA Processing Machines

08:30-08:45amBacterial Ribonucleoprotein bodies (BR-bodies) organize mRNA decay and coordinate other steps of RNA metabolism in bacteria
Vidhyadhar Nandana, Luis A. Ortiz Rodrguez, Julie S Biteen, Ali Hatami, Kaveendya S Mallikaarachchi, Yingxi Elaine Zhu, Katherine Lopez, Seth W Childers, Jared M Schrader
Departments of Chemistry and Biological Sciences, Wayne State University
08:45-09:00amData-driven maps of RNA polymerase III transcription and macromolecular interactions identifies new gene targets and regulatory mechanisms
Rajendra KC, Ruiying Cheng, Sihang Zhou, Simon Lizarazo, Duncan Smith, Kevin Van Bortle
Center of Biophysics and Quantitative Biology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA
09:00-09:15amHuman CCR4-NOT is a global regulator of gene expression and is a novel silencer of retrotransposon activation
Shardul Kulkarni, Alexis Morrissey, Courtney Smith, Oluwasegun T. Akinniyi, Shaun Mahony, Aswathy Sebastian, Istvan Albert, Cheryl A. Keller, Belinda Giardine, Istvan Albert, Alexei Arnaoutov, Joseph C. Reese
Center for Eukaryotic Gene Regulation and Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA
09:15-09:30amCharacterization of the UPF1 protein interactome in yeast provides mechanistic insight into mRNP transitions during nonsense-mediated mRNA decay
Sarah LH Nock, Kristian E Baker
Department of Genetics and Genome Sciences, Case Western Reserve University
09:30-09:45amMapping the transcriptional effects of the ER stress sensor IRE1 with optogenetic oligomerization and long-read sequencing
Jacob W. Smith, Vladislav Belyy
Department of Chemistry and Biochemistry, The Ohio State University
09:45-10:00amGCN2 monitors mRNA translation termination
Katharine R. Maschhoff, Kailey Worner, Gabrielle M. Schuh, Wenqian Hu
Department of Biochemistry and Molecular Biology, Mayo Clinic
10:00-10:30amCoffee break
  

Session IV: Session 4:RNA emerging themes

10:30-10:45amPredictive computational method development for T-box riboswitch drug discovery
Emily A. Fairchild, Destini McCartney, Danushika Hearth, Sebastian Schmutzler, Ralf Hoffmann, Jennifer V. Hines
Department of Chemistry & Biochemistry, Ohio University & Department of Chemistry, Leipzig University
10:45-11:00amConstruction of RNA four-way junction to co-deliver RNAi and chemical drugs for efficient treatment of colon cancer lung metastasis with undetectable toxicity
Kai Jin, Xin Li, Peixuan Guo
Division of Pharmaceutics & Pharmacology, College of Pharmacy; Center for RNA Nanotechnology and Nanomedicine; The Ohio State University, Columbus, OH, United States.
11:00-11:15amCASC15 lncRNA as a Mediator of Vascular Senescence in the Renin-Angiotensin System
Warlley Rosa Cunha, Maria Martin de la Vega, Anika Kulkarni, Delphine Gomez, Cristina Espinosa-Diez
Center for Molecular Medicine and Genetics Wayne State University, Detroit, MI
11:15-11:30amTitle not published online - please see booklet
Tiffany Barwell
University of North Carolina at Charlotte
11:30-11:45amPurine mRNA modifications impact translation speed
Rachel Giles, Tyler Smith, Kristin Koutmou
Chemistry, University of Michigan
11:45-12:00pmSelective Small Molecule Targeting of Homologous RNA-Binding Proteins
Johann M. Roque, Julia A. Haas, Beth P. Anderson, Ariel J. Thelander, Blanton S. Tolbert, Brittany S. Morgan
Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN
  
12:00-12:30pmAwards and Closing Remarks