2007 Rustbelt RNA Meeting







Friday, Oct 19
12:00-01:00pmMeeting Registration (Foyer)
01:00-01:10pmOpening Remarks
Session I: Regulation and Stability
01:10-01:30pmProbing Functions for Son in Nuclear Speckle Structure and Gene Expression.
Alok Sharma, Sapna Varia, Athanasios Bubulya, Paula A. Bubulya
Biomedical Sciences Ph.D. Program, Department of Biological Sciences, Wright State University
01:30-01:50pmCoupling of ATP binding and hydrolysis to duplex unwinding by the DEAD-box protein Ded1p
Fei Liu, Huijue Jia, Eckhard Jankowsky
Department of Physics,Case Western Reserve University, Cleveland, OH
01:50-02:10pmRegulation of translation by mRNA decapping factors
Wenqian Hu, Thomas Sweet, Jeff Coller
Center for RNA Molecular Biology, Casee Western Reserve Univesrity
02:10-02:30pmCoffee break (short PI meeting in auditorium)
Session II: miRNA
02:30-02:50pmA lentiviral-based genetic library for microRNA and its applications
Zhongxin Lu, Yanglong Zhu, Yong Li
Department of Biochemistry and Molecular Biology
02:50-03:10pmMicroRNA hsa-mir-346 As A Schizophrenia Susceptibility Gene
Yanglong Zhu
Department of Biochemistry and Molecular Biology, and Center for Genetics and Molecular Medicine, School of Medicine, University of Louisville
03:10-06:00pmPoster Session
03:20-04:40pmodd numbers present
04:40-06:00pmeven numbers present
06:00-07:00pmDinner (Upstairs in the Mezzanine)
Session III: tRNA
07:10-07:30pmDeterminates of Binding and Editing of the Adenosine to Inosine tRNA editing complex from Trypanosoma brucei
Frank Ragone, Otavio Thiemann, Jessica Wohlgamuth-Benedum, Juan Alfonzo
Microbiology The Ohio State University
07:30-07:50pmRole of the P/E state in ribosomal translocation
Sarah E. Walker, Kurt Fredrick
Department of Microbiology, The Ohio State University
07:50-08:10pmC to U Editing at Position 32 of the Anticodon Loop Precedes tRNA 5' Leader Removal in Trypanosomatids
Kirk W. Gaston, Mary-Anne T. Rubio, Jessica L. Spears, Irena Pastar , F. Nina Papvasiliou, Juan D. Alfonzo
Microbiology, The Ohio State University
08:10-08:30pmThe Effect of Oxidative Stress on the Levels of tRNA Modifications
Peter Palenchar
Dept. of Chemistry; Rutgers University-Camden
08:30-08:50pmProbing the mechanism and substrate specificity of the unusual 3'-5' polymerization reaction catalyzed by the tRNAHis guanylyltransferase (Thg1)
Jane E Jackman, Eric M Phizicky, Sasha Lebedev
Biochemistry, The Ohio State University
08:50-09:10pmCoffee break
Session IV: pRNA
09:10-09:30pmInstrumentation and metrology for single RNA counting in biological complexes or nanoparticles by a single-molecule dual-view system
Hui Zhang, Dan Shu, Faqing Huang, Peixuan Guo
Department of Biomedical Engineering, University of Cincinnati
09:30-09:50pmEngineering of an active artificial bacteriophage phi29 pRNA
Feng Xiao, Nick Snead, Hui Zhang, Peixuan Guo
Department of Biomedical Engineering, University of Cincinnati
09:50-10:10pmInteraction with pRNA and DNA-dependent ATP hydrolysis of gp16 of bacterial virus phi29 DNA packaging motor
Tae Jin Lee, Hui Zhang, Peixuan Guo
Department of Biomedical Engineering, University of Cincinnati
10:10-10:20pmPresentation of the Poster Awards
10:20-12:00amEvening Reception (Central Lobby Area)
All PIs - please stay in the auditorium for the RRM08 planning meeting
Saturday, Oct 20
07:10-08:10amContinental Breakfast (Rafter's Restaurant with Coupon)
Session V: RNA splicing
08:20-08:40amFOX, SF1 and SR proteins cooperate directly in the assembly of U2AF and the prespliceosomal E complex
Hua-Lin Zhou, Hua Lou
Department of Genetics, Case Western Reserve University
08:40-09:00amElucidating a role for Btf in pre-mRNA transcription and splicing
Sapna Varia, Zhihui Deng, Alok Sharma, Dr.Tom Bubulya, Dr.Paula Bubulya
Biomedical Sciences, Wright State University
09:00-09:20amYeast SUV3 Promotes Group I Intron Splicing by Recycling Co-factors from Excised Intron RNPs
Edward M. Turk, Alycia Conway, Mark G. Caprara
The Center for RNA Molecular Biology - Case Western Reserve University
09:20-09:40amMolecular mechanism of genotoxic stress induced alternative splicing of MDM2
Ravi K Singh, Dawn S Chandler
Center for Childhood Cancer,Childrens Research Institute and department of pediatrics, The Ohio State University, Columbus, OH.
09:40-10:00amRegulation of NF1 Alternative Splicing By CELF Proteins
Victoria A. Barron, Hui Zhu, Andrea N. Ladd, Hua Lou
Department of Genetics, Case Western Reserve University
10:00-10:20amCoffee break
Session VI: RNA structure
10:20-10:40amStructural studies of the Bacillus subtilis T box antiterminator/tRNA model complex
John A. Means, Crystal M. Simson, Jeffrey J. Rack, Jennifer V. Hines
Chemistry and Biochemistry, Ohio University
10:40-11:00amActive Site Architecture and Global Stability of the Hairpin Ribozyme
Mark A. Ditzler, Nils G. Walter
Biophysics University of Michigan
11:00-11:20amConformationally restricted nucleotides as a biophysical probe of RNA thermodynamics, catalysis, and protein binding
Minako Sumita, Kristine R. Julien, Po-Han Chen, Ite Laird-Offringa, Charles G. Hoogstraten
Department of Biochemistry and Molecular Biology, Michigan State University
11:20-11:40amMapping the in situ RNA binding specificity of the SR protein SF2/ASF using CLIP-Seq
Jeremy Sanford, Xin Wang, Xinguo Wang, Yunlong Liu
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine
11:40-12:00pmMechanism of the hairpin ribozyme: Thermodynamics and kinetics of intermolecular domain docking
Charles G. Hoogstraten, Minako Sumita, Kristine R. Julien
Biochemistry & Molecular Biology, Michigan State University
12:00-12:20pmClosing Remarks and Presentation of the Oral Awards