Agenda
Friday, Oct 23
| Time | Event |
|---|---|
| 11:00-01:00pm | Registration |
Session I: A Day In The Life Of An RNA Part I: Biosynthesis, Processing, and Export | |
| 12:45-01:00pm | Welcome and Opening Remarks |
| 01:00-01:15pm | Antagonistic splicing factors hnRNP A1 and SRSF2 compete for binding to snRNA 7SK Daniel C. Totten, Andrea J. Berman Department of Biological Sciences, University of Pittsburgh |
| 01:15-01:30pm | ESRP2 controls an adult splicing program in hepatocytes to support postnatal liver maturation Amruta Bhate, Darren J. Parker, Thomas W. Bebee, Jaegyoon Ahn, Russ P. Carstens, Auinash Kalsotra Department of Biochemistry and Medical Biochemistry, University of Illinois, Urbana Champaign |
| 01:30-01:45pm | The chromatin remodeling complex SWI/SNF is a master regulator of meiotic splicing in S. cerevisiae Srivats Venkataramanan, Stephen Douglass, Anoop Raj Galivanche, Suman K Pradhan, Tracy L Johnson Department of Molecular Cell and Developmental Biology, UCLA |
| 01:45-02:00pm | Unexpected mechanistic features of a multifunctional tRNA methyltransferase Aiswarya Krishnamohan, Jane E. Jackman Dept. of Chemistry and Biochemistry, Center for RNA Biology, The Ohio State University |
| 02:00-02:15pm | Title not published online - please see printed booklet Zhao J, Lin H-C, Niland CN, Jankowsky E, Harris ME Department of Biochemistry, CWRU School of Medicine, Cleveland, OH 44109 |
| 02:15-02:30pm | Identification of novel proteins involved in nuclear export of pre-tRNAs in Saccharomyces cerevisiae Kunal Chatterjee, Jingyan Wu, Yao Wan, Anita Hopper Department of Molecular Genetics, The Ohio State University |
| 02:30-02:45pm | Direct interaction and functional coupling of the DEAD-box RNA helicases, eIF4A and Ded1p, from Saccharomyces cerevisiae Zhaofeng Gao, Andrea Putnam, Heath Bowers, Ulf-Peter Guenther, Xuan Ye, Angela Hilliker, Eckhard Jankowsky Center for RNA Molecular Biology and Department of Biochemistry, Case Western Reserve University, Cleveland, OH |
| 02:45-03:15pm | Coffee Break |
Session II: RNA Structure, Biophysics, and Recognition | |
| 03:15-03:30pm | Determinants of specific recognition of mischarged Ala-tRNAPro by a bacterial trans-editing domain Eric M. Danhart, Lexie Kuzmishin, Brianne Sanford, Marina Bakhtina, Marija Kosutic, Ronald L. Micura, Karin Musier-Forsyth, Mark P. Foster Department of Chemistry and Biochemistry, The Ohio State University |
| 03:30-03:45pm | High-throughput RNA 3D motif structure prediction and validation Jian Wu, Cuiji Zhou, Ying Wang, James Li, Annie Showers, Dana Drivera, Neocles B. Leontis, Craig L. Zirbel, David M. Bisaro, Biao Ding Department of Molecular Genetics, Center for RNA Biology, Molecular, Cellular, and Developmental Biology Program, The Ohio State University, Columbus, OH 43210 USA |
| 03:45-04:00pm | A Riboswitch-Containing sRNA Controls Gene Expression by Sequestration of a Response Reg Margo P Gebbie, Sruti Debroy, Jonathan Goodson, Arati Ramesh, Danielle Garsin, Wade Winkler Cell Biology and Molecular Genetics, University of Maryland |
| 04:00-04:15pm | A mechanistic and structural study of a yet uncharacterized RNA sensor: the ykkCD riboswitch Beau Champ, Ambar Rana, Nicholas Frecker, Delores James, Timea Gerczei Ball State University |
| 04:15-04:30pm | Title not published online - please see printed booklet Bradley P. Klemm, Kipchumba J. Kaitany, Michael J. Howard, Adam Z. Thelen, Allison J.L. Dewar, Matthew J. Henley, Carol A. Fierke Biological Chemistry, University of Michigan |
| 04:30-04:45pm | Structural insights into how the tandem RRMs of hnRNP A1 bind RNA stem loops Christopher E. Morgan, Jennifer L. Meagher, Jeffrey D. Levengood, Carrie Rollins, James Delproposto, Jeanne A. Stuckey, Blanton S. Tolbert Department of Chemistry, Case Western Reserve University |
| 04:45-05:00pm | Structural analysis of the Ccq1-Tpz1-Poz1 telomere subcomplex in fission yeast Harry Scott Department of Pharmacology, Case Western University |
| 05:00-05:10pm | Stretch Break |
Session III: Keynote Lecture, Dr. Ronald Breaker | |
| 05:15-06:20pm | Dr Ronald Breaker (Yale University and HHMI) Prospects for Ribozyme and Riboswitch Discovery |
| 06:20-06:30pm | PI Meeting and Additional Poster Setup |
| 06:30-07:30pm | Dinner (Wilderness Hall North) |
| 07:30-09:00pm | Poster Session I Odd number posters attended |
| 09:00-10:30pm | Poster Session II Even number posters attended |
Saturday, Oct 24
| Time | Event |
|---|---|
| 06:30-08:30am | Breakfast (Wilderness Hall North) |
Session IV: A Day In The Life Of An RNA Part II: Translation and Decay | |
| 08:30-08:45am | Alternative translation initiation site usage under environmental stress conditions. Pieter Spealman, Joel McManus Department of Biological Sciences, Carnegie Mellon University |
| 08:45-09:00am | Translation initiation is controlled by RNA folding kinetics via a ribosome drafting mechanism Amin Espah Borujeni, Howard M. Salis Chemical Engineering, Penn State University |
| 09:00-09:15am | ATP hydrolysis by Upf1 promotes efficient translation termination on substrates of the nonsense-mediated mRNA decay pathway in yeast Lucas D. Serdar, Dajuan Whiteside, Kristian E. Baker Center for RNA Molecular Biology, Case Western Reserve University |
| 09:15-09:30am | The life and times of transcribed RNA as told through global nascent RNA sequencing Brian Magnuson, Artur Veloso, Michelle Paulsen, Frederick Derheimer, Zahid Bonday, Mats Ljungman School of Public Health Environmental Health Sciences, University of Michigan, Ann Arbor, MI |
| 09:30-09:45am | The naturally-occurring non-stop mRNAs from Arabidopsis display relatively low stability Laura de Lorenzo , Arthur G. Hunt Dept. of Plant and Soil Sciences, University of Kentucky, Lexington, KY, 40546-0312, USA. |
| 09:45-10:00am | ADARs Antagonize Deadenylase-dependent Destabilization of a Nuclear-retained RNA Aparna Anantharaman, Vidisha Tripathi, Kannanganattu V. Prasanth, Abid Khan, Supriya G. Prasanth, Je-Hyun Yoon, Myriam Gorospe, Johan Ohlson, Helene Wahlstedt, Marie Ohman, Shuomeng Guang, Jian Ma, Jochen C. Hartner, Shinichi Nakagawa, Tetsuro Hirose, Michael F. Jantsch Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign |
| 10:00-10:15am | Alternative exon junction complexes differentially mark mRNAs targeted for Nonsense Mediated mRNA Decay Lauren Woodward, Justin Mabin, Guramrit Singh Molecular Genetics The Ohio State University |
| 10:15-10:45am | Coffee Break |
Session V: RNA in Disease, RNA in Health, and RNA in Biotechnology | |
| 10:45-11:00am | Relocalization of Human Lysyl-tRNA Synthetase following HIV-1 Infection: Implications for tRNA Primer Recruitment Alice Duchon , Nathan Titkemeier, Corine St. Gelais, Li Wu, Karin Musier-Forsyth Department of Chemistry and Biochemistry, Center for RNA Biology, Center for Retroviral Research, The Ohio State University, Columbus, OH 43210 |
| 11:00-11:15am | Characterizing the role of DDX41, a DEAD-box RNA helicase, in blood cancer and the spliceosome James M. Hiznay, Chantana Polprasert, Hideki Makishima, Xiaorong Gu, Yogen Saunthararajah, Carsten Mller-Tidow, Eckhard Jankowsky, Jaroslaw P. Maciejewski, Richard A. Padgett Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic |
| 11:15-11:30am | Mechanisms of unconventional translation initiation at CGG repeats in the Fragile X mRNA, FMR1. Michael G. Kearse, Katelyn M. Green, Amy Krans, Caitlin M. Rodriquez, Alexander E. Linsalata, Aaron C. Goldstrohm, Peter K. Todd Dept. of Neurology, Dept. of Biological Chemistry, University of Michigan |
| 11:30-11:45am | Enhanced MicroRNA Detection Assays Based on Tyramide Signal Amplification and GammaPNA Probes. Munira Fouz , Lauren Xu , Danith Ly , Veronica Hinman , Subha R. Das , Bruce Armitage Department of Chemistry, Carnegie Mellon University |
| 11:45-12:00pm | RNA as a unique polymer to build functional nanostructures for material and biomedical applications Hui Li, Peixuan Guo Nanobiotechnology Center, Markey Cancer Center, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536 |
| 12:00-12:15pm | Stretch Break |
Session VI: Principal Investigator Presentations | |
| 12:15-12:35pm | Mechanism of PWI Motif Binding to Nucleic Acids Harry Chanzu, Elizabeth I. Lopez, Denise Flores, Blair R. Szymczyna Dept. of Chemistry, Western Michigan University |
| 12:35-12:55pm | Silencing of a telomeric gene by a noncoding RNA derived from its own 3’-UTR Jayakrishnan Nandakumar, Kamlesh Bisht Molecular Cellular and Developmental Biology, University of Michigan |
| 12:55-01:15pm | Closing Remarks and Award Presentations |