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Friday, Oct 14

10:00-12:30pmWorkshop 2 Mining the Great "Omics" Data Harvest
10:00-12:30pmWorkshop 1 Deliberate Engagement
01:00-01:15pmWelcome and opening remarks

Session I: RNA Structure and Function

01:15-01:30pmLinking local RNA structural dynamics to ribosome binding in the prfA RNA thermosensor
David Beier, Elizabeth Duran, Nils Walter, Sarah Keane
Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA
01:30-01:45pmTitle not published online - please see booklet
Huaqun Zhang, Audrey Kehling, GeunYoung Sim, Andrew Savidge, Jackson Secor, Kotaro Nakanishi
Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio, US
01:45-02:00pmA study of non-templated polymerization for understanding the emergence of RNA from prebiotic mixtures
Xiwen Jia, Stephanie J. Zhang, Lijun Zhou, Jack W. Szostak
Department of Chemistry and Chemical Biology, Harvard University
02:00-02:15pmSHAPE probing of the HIV-1 Reverse Transcriptase Initiation Complex reveals RNA flexibility changes adjacent to the Primer-Binding Site
Chathuri Pathirage, William Cantara, Steven Tuske, Eddy Arnold, Karin Musier-Forsyth
Center for Retrovirus Research, Center for RNA Biology, Department of Chemistry and Biochemistry, The Ohio State University
02:15-02:30pmFluorogenic U-rich internal loop (FLURIL) tagging with bPNA enables intracellular RNA and DNA tracking
Yufeng Liang, Sydney Willey, Yu-Chieh Chung, Yi-Meng Lo, Shiqin Miao, Sarah Rundell, Li-Chun Tu, Dennis Bong
Department of Biological Chemistry and Pharmacology, The Ohio State University
02:30-02:45pmTemperature-sensitive RNAs: flanking sequence of a known RNA thermometer (RNAT) and identification of novel RNATs genome-wide
Elizabeth A. Jolley, Kathryn M. Bormes, Helen Yahknin, David C. Tack, Paul Babitzke, Philip C. Bevilacqua
Department of Chemistry, Pennsylvania State University
02:45-03:15pmCoffee Break

Session II: Regulation

03:15-03:30pmMicroRNAs Have Macro Impacts on the Regulation of Alternative Splicing
Whitney D. Jimenez, Hannah R. Ackerman, Matias Montes, Dawn Chandler
Center for Childhood Cancer and Blood Disorders, Nationwide Childrens Hospital
03:30-03:45pmtRNA introns: A novel class of small non-coding regulatory RNAs
Regina Nostramo, Anita K. Hopper
Department of Molecular Genetics, The Ohio State University
03:45-04:00pmArginine methylation of Puf4 drives diverse protein functions
Murat C. Kalem, Sean Duffy, Shichen Shen, Jan Naseer Kaur, Jun Qu, John C. Panepinto
Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY, USA & University of California, San Francisco, CA
04:00-04:15pmQuantitative and systematic definitions of inherent specificities of RNA binding proteins
Soon Yi, Xuan Ye, Eckhard Jankowsky
Department of Biochemistry and Center for RNA Science and Therapeutics, School of Medicine, Case Western Reserve University, Cleveland, OH
04:15-04:30pmMetabolites can bind and regulate human 5′UTRs
Jeffrey T. Morgan, Kevin G. Hicks, Jared Rutter
Howard Hughes Medical Institute, Department of Biochemistry, University of Utah
04:30-04:40pmLogistics Talk
04:45-05:45pmKeynote Lecture from Dr. Anita Hopper "The Lives and Deaths of tRNAs and Their Introns"
06:15-07:45pmDinner & Poster Setup
07:45-09:15pmPoster Session (odd number posters manned and judged)
08:00-11:00pmCocktails and Reception
09:15-10:45pmPoster Session (even number posters manned and judged)

Saturday, Oct 15


Session III: RNA Processing, Translation, and Decay

08:45-09:00amRESC8 and RESC14 cooperate to mediate RESC function and dynamics during trypanosome RNA editing
Katherine Sortino, Brianna Tylec, Natalie M. McAdams, Runpu Chen, Yijun Sun, Laurie K. Read
Department of Microbiology & Immunology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY 14203.
09:00-09:15amIdentification of a tRNA-specific function for the tRNA methyltransferase Trm10 in Saccharomyces cerevisiae
Isobel Bowles, Aiswarya Krishnamohan, Abi Hubacher, Jane Jackman
Ohio State Biochemistry Program
09:15-09:30amCleavage and Polyadenylation Specificity Factor (CPSF30) involved in plant immunity system
Lichun Zhou, Huazhen Liu, Pradeep Kachroo, Arthur G. Hunt
Department of Plant and Soil Sciences, University of Kentucky, Lexington KY 40546, USA
09:30-09:45amDynamic Phosphorylation Of RNA Helicase eIF4A Mediates Translational Responses To Cell Cycle Transitions And Nutrients Starvation
Ansuman Sahoo, Qian He, Marium Ashraf, Samantha Nelson, Gerald Koudelka, Shichen Shen, Jun Qu, Robert A. Zollo, Joseph Barbi, Sarah E. Walker
Biological Sciences Department, University at Buffalo
09:45-10:00amPYM1 controls of Exon Junction Complex occupancy at canonical and non-canonical positions and can thereby modulate NMD
Manu Sanjeev, Lauren Woodward, Robert Patton, Ralf Bundschuh, Guramrit Singh
Molecular Genetics, The Ohio State University
10:00-10:15amThe role of KPAP1 methylation in moderating mitochondrial mRNA 3’ tail addition in Trypanosoma brucei
Clara M. Smoniewski, Poorya Mirzavand Borujeni, Marshall Hampton, Reza Salavati, Sara L. Zimmer
Dept. of Biomedical Sciences, U of MN Medical School, Duluth campus
10:15-10:30amTitle not published online - please see booklet
Benjamin Pastore, Hannah L. Hertz, Jillian A. Wagner, Ian F. Price, Wen Tang
Department of Biological Chemistry and Pharmacology, The Center for RNA Biology, The Ohio State Biochemistry Program, The Ohio State University
10:30-11:00amCoffee Break

Session IV: Development & Disease

11:00-11:15amPhase separation of demethylase LSD1 enriches lncRNA TERRA on telomeres to promote R-loop formation for telomere maintenance in ALT cancer cells
meng xu, Dulmi Senanayaka, David Chenoweth, Nicholas J Reiter, Huaiying Zhang
Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University
11:15-11:30amThe mRNA regulatory function of Brat is essential for development and neurogenesis
Robert P. Connacher, Yichao Hu, Michael B. OConnor, Xiaohang Yang, Howard D. Lipshitz, Richard T. Roden, Aaron C. Goldstrohm
Dept. Biochemistry, Molecular Biology, & Biophysics, University of Minnesota
11:30-11:45amMyotonic Dystrophy Type 1 Adversely Alters affects Liver Function and Liver Lipid Synthesis
Zac Dewald, Auinash Kalsotra
Biochemistry, University of Illinois
11:45-12:00pmTitle not published online - please see booklet
Eng-Soon Khor , Feng Jiang, Omar M. Hedaya, Waihong Wilson Tang, Peng Yao
Aab Cardiovascular Research Institute , University of Rochester
12:00-12:20pmRepeat G4 RNA structures preferentially interact with the Lysine Specific Demethylase-1-CoREST complex, mask nucleosome recognition, and trigger phase separation.
Dulmi Senanayaka, Meng Xu, William J Martin, Owen Schneider, Manuel Ascano, Jr, Nick Reiter
Department of Chemistry, Marquette University
12:20-12:40pmTracking single chromosome localization, orientation, and movement in living cells by fluorescent guide RNAs
Yu-Chieh Chung , Madhoolika Bisht, Li-Chun Tu
Department of Biological Chemistry and Pharmacology, The Ohio State University
12:40-12:55pmAwards and closing remarks