Friday, Oct 17

11:00-12:45pmHotel check-in and registration (boxed lunches available for those who preordered)
12:45-01:00pmWelcome and opening remarks

Session I: Oral Session I: Transcription, mRNA processing & regulation
CHAIR: Jo Ann Wise, Case Western Reserve University
Grand Ballroom

01:00-01:12pmSelectivity in substrate binding by the exonuclease Rrp6p
Armend Axhemi, Sukanya Srinivasan, Elizabeth Wasmuth, Christopher Lima, Eckhard Jankowsky
Center for RNA Molecular Biology, Case Western Reserve University
01:12-01:24pmCELF1 is necessary for myofibril organization and cardiac morphology during embryonic development
Yotam Blech-Hermoni, Michael W. Jenkins, Oliver Wessely, Andrea N. Ladd
Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine
01:24-01:36pmPnrc2 is required for rapid decay of oscillating transcripts via their 3’ UTR
Thomas L. Gallagher, Nicolas L. Derr, Kiel T. Tietz, Courtney E. French, Jasmine M. McCammon, Michael L. Goldrich, Steven E. Brenner, Sharon L. Amacher
Molecular Genetics, The Ohio State University
01:36-01:48pmMechanistic insight into the association of the NMD factor, Upf1p, with mRNA in Saccharomyces cerevisiae
DaJuan L. Whiteside, Kristian E. Baker
Center for RNA Molecular Biology, Case Western Reserve University
01:48-02:00pmSignificance of novel RNA-protein interaction in U12-dependent splicing
Jagjit Singh MS, Kavleen Sikand Ph.D., Tupa Basu Roy M.S, Girish C. Shukla Ph.D.
Center of Gene Regulation in Health and Disease, Cleveland State University, Cleveland, OH-44115
02:00-02:12pmConformational control of the U2 snRNA by Cus2p
Sandy Tretbar, Aaron A. Hoskins
a University of Wisconsin-Madison, Biochemistry Department, 433 Babcock Dr, Madison, WI, 53706
02:12-02:24pmPhosphorylation regulates assembly of cancer-relevant splicing factors SF3b155 and SPF45
Jake A. Kloeber, Sarah Loerch, Clara L. Kielkopf
Center for RNA Biology, University of Rochester Medical Center, Rochester, NY
02:24-02:36pmCodon optimization is a major determinant of mRNA half-life in Saccharomyces cerevisia
Vladimir Presnyak, Ying-Hsin Chen, Sophie Martin, Najwa Al Husaini, Nicholas Kline, Nathan Morris, Sara Olson, Brenton Graveley, Kristian Baker, Jeff Coller
Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, OH
02:36-02:48pmNusA-dependent transcription termination in bacteria
Smarajit Mondal,, Alexander V. Yakhnin, Paul Babitzke
Dept. of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, Pennsylvania State University
02:48-03:00pmNumerous C/D box snoRNAs are associated with the spliceosome, form non-canonical ribonuclear protein complexes and regulate alternative splicing
Marina Falaleeva , Amadis Pages, Zaneta Matuszek, Eduardo Eyras, Ruth Sperling , Stefan Stamm
Biochemistry, University of Kentucky, USA
03:00-03:30pmCoffee Break

Session II: Oral Session II: RNA at the Chemistry - Biology Interface
CHAIR: Andrey Krasilnikov, Pennsylvania State University
Grand Ballroom

03:30-03:42pmRegulation of the RNA-Activated Protein Kinase (PKR) by Highly Structured Direct and Indirect Bacterial Riboswitches
Chelsea Hull, Philip C. Bevilacqua
Chemistry and Center for RNA Molecular Biology
03:42-03:54pmPhylogenetic, Structure and thermodynamic insight of HIV-1 Intronic splicing silencer (ISS)
Niyati Jain, Brittany D. Rife, Christopher E. Morgan , Blanton S. Tolbert
Department of Chemistry, Case Western Reserve University
03:54-04:06pmNext-generation tools for RNA enzymology: Determination of rate and equilibrium constants for large populations of RNA substrate variants using high throughput sequencing.
Hsuan-Chun Lin, Courtney Niland, Jing Zhao, David R. Anderson, Eckhard Jankowsky, Michael E. Harris
Department of Biochemistry, School of Medicine, Case Western Reserve University
04:06-04:18pmEntropy As a Key Factor for One Step Formation of Phi29 pRNA 3WJ from Three RNA Fragments
Daniel Binzel, Emil Khisamutdinov, Peixuan Guo
Nanobiotechnology Center, Markey Cancer Center, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA
04:18-04:30pmDRBD18 is an essential Trypanosome RNA binding protein that modulates RNA abundance and is regulated by arginine methylation
Kaylen Lott, Shreya Mukhopadhyay, Jie Yao , Jun Li, Jun Qu, Yijun Sun, Laurie Read
Microbiology and Immunology, SUNY at Buffalo
04:30-04:42pmTitle not published online - please see printed booklet
Gayan Mirihana Arachchilage , Arosha C. Dassanayake , Soumitra Basu
Department of Chemistry and Biochemistry, Kent State University
04:42-04:54pmDissecting miRNA function and localization using single molecule approaches
Laurie A. Heinicke, Sethuramasundaram Pitchiaya, Elizabeth L. Cameron, Nils G. Walter
Chemistry, University of Michigan
04:54-05:06pmNovel functions of cytochrome C in the cellular response to stress
Raul Jobava, Mridusmita Saikia, Andrea Putnam, Tao Pan, Eckhard Jankowsky, Maria Hatzoglou
Department of Biochemistry, Case Western Reserve University, Cleveland, OH
05:06-05:18pmMultiple Conformational Sampling Achieved By Alternate Base-Pairing in Loop A of the Hairpin Ribozyme
Patrick Ochieng, BeiBei Wang, Michael Feig, Charles Hoogstraten
Michigan State University
05:18-05:30pmUsing Protein mRNA tethering to identify novel splicing factors
Benjamin Cieply, Russ Carstens
Department of Genetics, Perelman School of Medicine, Univeristy of Pennsylvania
05:30-06:00pmBreak (outside of Grand Ballroom)/PI Meeting (The Rivers Room)

Session III: Keynote Speaker Lecture: Professor Manuel Ares, Jr, Univ of California Santa Cruz
Introduction by John Woolford, Carnegie Mellon
Grand Ballroom


Session IV: Poster Session I
Marquis B Ballroom and Marquis C Ballroom

08:45-12:00pmCocktail Connection (Beer, cocktails, colleagues & other refreshments) -only beer available during poster session

Saturday, Oct 18


Session V: Oral Session III: RNAs in Translational Control
CHAIR: Jon Dinman, University of Maryland
Grand Ballroom

08:30-08:42amRibosomal proteins influence RNA dynamics during 30S assembly
Sanjaya Abeysirigunawardena, Hajin Kim, Taekjip Ha, Sarah Woodson
T. C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore MD
08:42-08:54amTitle not published online - please see printed booklet
Rohan Balakrishnan, Kenji Oman, Ralf Bundschuh, Kurt Fredrick
Ohio State Biochemistry Program
08:54-09:06amEukaryote-specific extensions of ribosomal proteins are involved in 60S ribosomal subunit assembly
Beril Kumcuoglu, Jelena Jakovljevic, John L. Woolford
Carnegie Mellon University
09:06-09:06amRibosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and NMD.
Ashton T Belew, Arturas Meskauskas, Sharmishtha Musalgaonkar, Vivek M Advani, Jonathan D Dinman
University of Maryland
09:18-09:30amEF-P Dependent Pauses Integrate Proximal and Distal Signals during Translation
Sara Elgamal, Assaf Katz, Steven J. Hersch, David Newsom, Peter White, William W. Navarre, Michael Ibba
Microbiology, The Ohio State University
09:30-09:42amBase pair recognition by the Thg1 family 3'-5' polymerases
Krishna J Patel, Paul Yourik, Jane E Jackman
Chemistry and Biochemistry,The Ohio State University
09:42-09:54amCap homeostasis is independent of poly(A) tail length
Daniel L. Kiss, Kenji Oman, Julie A. Dougherty, Chandrama Mukherjee, Ralf Bundschuh, Daniel R. Schoenberg
Center for RNA Biology, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio 43210
09:54-10:06amTitle not published online - please see printed booklet
Katherine M. Anderson, Ian M.C. Fleming, Kirk W. Gaston, Pat A. Limbach, Mary Anne Rubio, Juan D. Alfonzo
Department of Microbiology and OSU Center for RNA Biology, The Ohio State University, Columbus, 43210 Ohio, USA
10:06-10:18amRibosome release from non-stop mRNAs is essential
Heather A. Feaga, Kenneth C. Keiler
Department of Biochemistry and Molecular Microbiology, Pennsylvania State University
10:18-10:30amPotential for novel regulation via AUG triplets at the 5’ termini of canonical leadered mRNAs of Escherichia coli
Heather Beck, Ian Fleming, Gary Janssen
Miami University

Session VI: Poster Session II
Marquis B Ballroom and Marquis C Ballroom

12:30-02:00pmLunch/Career Round Table

Session VII: Oral Session IV: RNomics, Noncoding RNAs & Diseases
CHAIR:Scott Showalter, Pennsylvania State University
Grand Ballroom

02:00-02:12pmHelical Defects in MicroRNA Influence Protein Binding by TAR RNA Binding Protein
Roderico Acevedo, Nichole Orench-Rivera, Kaycee A. Quarles, Scott A. Showalter
The Pennsylvania State University
02:12-02:24pmHIV-1 alters host cellular gene expression in target cell specific manner through microRNA regulation
Debjani Guha, Allison Mancini, Jessica Sparks, Velpandi Ayyavoo
IDM, University of Pittsburgh
02:24-02:36pmTitle not published online - please see printed booklet
Priscilla Wong, Kausik Chakrabarti
CNAST, Department of Chemistry, Carnegie Mellon University
02:36-02:48pmGlobal analysis of RNA-protein interaction site and RNA secondary structure dynamics in response to the plant hormone abscisic acid
Matthew R. Willmann, Mengge Shan, Fan Li, Alsu Ibragimova, Sarah Foster, Brian D. Gregory
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
02:48-03:00pmComprehensive annotation of Physcomitrella patens small RNA loci reveals 23nt heterochromatic siRNAs dependent on a minimal Dicer-Like gene
Ceyda Coruh, Sung Hyun Cho, Saima Shahid, Qikun Liu, Andrzej Wierzbicki, Michael J. Axtell
Department of Biology, Penn State University
03:00-03:12pmHigh-throughput probing of human lncRNA secondary structure by Mod-seq
Yizhu Lin, Gemma E. May, C. Joel McManus
Department of Biological Sciences, Carnegie Mellon University
03:15-03:35pmThe LARP1-motif contains structurally conserved but sequence diverged repeats
Roni M. Lahr, Seshat M. Mack, Annie Heroux, Sarah P. Blagden, Andrea J. Berman
University of Pittsburgh, Department of Biological Sciences. Pittsburgh, PA 15260
03:35-03:55pmUncovering the RNA binding protein machinery associated with age and gender during liver development
Praneet Chaturvedi, Yaseswini Neelamraju, Waqar Arif, Auinash Kalsotra, Sarath Chandra Janga
Bio-Health Informatics, School of Informatics & Computing, Indiana University- Purdue University, Indianapolis
03:55-04:10pmClosing remarks and awards