Friday, Oct 26


Foyer 2nd floor

09:00-12:00pmWorkshop 1 — RNA structure visualization and analysis

Meeting Room 34

09:01-12:00pmWorkshop 2 — Graduate school applications

Meeting Room 35

01:00-01:15pmWelcome and opening remarks

Hayes Ballroom CDE

All Oral Sessions will be held in Hayes Ballroom CDE


Session I: RNA Shape, Structure and Recognition

Chair: Jessica Brown

01:15-01:30pmIn vivo RNA structural probing of uracil and guanine base pairing by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC)
David Mitchell III, Andrew J. Renda, Catherine A. Douds, Paul Babitzke, Sarah M. Assmann, Philip C. Bevilacqua
Department of Chemistry, Penn State University
01:30-01:45pmMaximizing quantitative structural information from high-throughput RNA structure probing
Molly E. Evans, Angela M Yu, Petr Sulc, Julius B. Lucks
Department of Chemical and Biological Engineering, Northwestern University
01:45-02:00pmTitle not published online - please see printed booklet
Jane K Frandsen, Anna V. Sherwood, Frank J. Grundy, Tina M. Henkin
Ohio State Biochemistry Program, Center for RNA Biology, The Ohio State University
02:00-02:15pmKIN-CLIP: transcriptome-wide kinetics for RNA-protein interactions in cells
Deepak Sharma, Leah Zagore, Matthew Brister, Carlos Crespo Hernandez, Donny Licatalosi, Eckhard Jankowsky
Center for RNA Science and Therapeutics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106
02:15-02:30pmTitle not published online - please see printed booklet
Audrey C. Kehling, Mi Seul Park, Alison E. Hager, Kotaro Nakanishi
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
02:30-02:45pmTitle not published online - please see printed booklet
Hiba A. Al-Ashtal, Courtney M. Rubottom, Andrea J. Berman
University of Pittsburgh
02:45-03:15pmCoffee break

Foyer 2nd floor


Session II: Sculpting the RNA: Processing and Modifications

Chair: Douglas Bernstein

03:15-03:30pmAccurate transcriptome-wide identification of m5C RNA modification events at single molecule resolution from direct RNA sequencing of human cell lines
Raja Shekar Varma Kadumuri, Mir Quoseena, Sarath Chandra Janga
Department of BioHealth Informatics, School of Informatics and Computing, Indiana University Purdue University
03:30-03:45pmDNA methylation regulates mRNA alternative cleavage and polyadenylation
Vishal Nanavaty, Changjing Hong, Elizabeth Abrash, Jeffrey M. Bhasin, Thomas J. Sweet , Tae Hyun Hwang, Angela H. Ting
Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic
03:45-04:00pmThe association of tRNA intron accumulation with environmental stress conditions
Lauren Peltier, Alicia Bao, Anita Hopper
Molecular Genetics, The Ohio State University
04:00-04:15pmAn orphan 3’-5’ polymerase implicated in noncoding RNA processing
Samantha Dodbele, Blythe Moreland , Yicheng Long, Ralf Bundschuh, Jane Jackman
Ohio State Biochemistry Program, The Ohio State University OSU; Center for RNA Biology, OSU
04:15-04:30pmMaturation of Drosophila intronic-RNase P RNA (RPR) critically depends on association with its protein subunits
Geeta Palsule, Venkat Gopalan, Amanda Simcox
Department of Molecular Genetics, The Ohio State University
04:30-05:00pmPoster Set up / PI Meeting
05:00-06:00pmKeynote Lecture — Dr Tom Cooper

"RNA processing impacts disease through multiple mechanisms"


Hayes Ballroom AB

07:45-09:15pmPoster session (odd number posters judged)

Foyer 2nd floor

09:00-12:00amCocktails and Reception

Foyer 2nd floor

09:30-11:00pmPoster session (even number posters judged)

Foyer 2nd floor


Saturday, Oct 27


Session III: Ribosome Assembly and Mechanisms of Translational Control

Chair: Angie Hilliker

08:45-09:00amFinal maturation stages of the polypeptide exit tunnel
Daniel Wilson, Amber LaPeruta, John L. Woolford
Biological Sciences Carnegie Mellon University
09:00-09:15amQuantitative analysis of yeast Kozak variants for AUG and near-AUG start codons using a massively parallel reporter assay
Christina Akirtava, Hunter Kready, Lauren Nazzaro, Gemma E. May, C. Joel McManus
Biological Sciences at Carnegie Mellon University
09:15-09:30amDiscovery and characterization of peptide inhibitors of RsmC function
Davidnhan To, Keshav GC, Dr. Sanjaya Abeysirigunawardena
Department of Chemistry and Biochemistry, Kent State University
09:30-09:45amRusty ribosomes: how oxidation damages rRNA and affects translation
Jessica Willi, Norbert Polacek, Pat A. Limbach
Department of Chemistry and Biochemistry, University of Bern
09:45-10:00amPseudouridylation of mRNA can alter translation elongation, fidelity and termination
Monika Franco, Daniel Eyler, Kristin Koutmou
Program in Chemical Biology, University of Michigan
10:00-10:15amRibosome binding by yeast eIF4B drives stress-induced changes in translation
Xiaozhuo LIU, Houtan Moshiri, Sarah E. Walker
Department of Biological Sciences, The State University of New York at Buffalo
10:15-10:30amMiR-574-FAM210A axis maintains cardiac mitochondrial translational homeostasis
Jiangbin Wu, Kadiam C Venkata Subbaiah, Feng Jiang, , Omar Hedaya, Wai Hong Wilson Tang, Peng Yao
Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine & Dentistry, Rochester, NY 14586
10:30-11:00amCoffee break

Foyer 2nd floor


Session IV: RNA in Health and Disease

Chair: Kausik Chakrabarti

11:00-11:15amMIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs
Qinyu Sun, Vidisha Tripathi, Deepak Singh, Qinyu Hao, Supriya G. Prasanth, Je-Hyun Yoon, Kyung-Won Min, Sylvia Davila, Richard W. Zealy, , Xiao Ling Li, Ashish Lal, Elin Lehrmann, Yongqing Zhang, Kevin G. Becker, Myriam Gorospe, Susan M. Freier, Kannanganattu Prasanth
Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign
11:15-11:30amDynamic regulation of alternative splicing of neurofibromatosis type 1 exon 23a in the mouse brain
Xuan Guo, Hua Lou
Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, 44106
11:30-11:45amLUC7L2 is a splicing regulatory protein that is frequently mutated in bone marrow neoplasms
Hershberger C.E., Gu, X., Dietrich, R.C., Hiznay J., Hosono N., Makishima, H. , Saunthararajah, Y., Maciejewski J. , Padgett R.A.
Cleveland Clinic Foundation, Cleveland, OH
11:45-12:00pmOverexpression of a non-muscle RBFOX2 splice isoform induces cardiac arrhythmias in Myotonic Dystrophy
Chaitali Misra, Sushant Bangru, Darren J. Parker, Sara Koenig, Ellen Lubbers, Peter Mohler, Jamila Hedhli, Wawrzyniec L. Dobrucki, Thomas A. Cooper, Auinash Kalsotra
Department of Biochemistry, University of Illinois, Urbana-Champaign, IL
12:00-12:15pmDDX3X Modulates CGG-Associated RAN Translation and Neuronal Toxicity
Alexander E. Linsalata, Fang He, Sam Natla, Peter K. Todd
University of Michigan
12:15-12:35pmHigh levels of intron-containing transcripts in aggressive cancers
Daniel Dominguez, Yi-Tsuan Tsai, Zefeng Wang, Christopher Burge
Pharmacology, UNC Chapel Hill
12:35-12:55pmRegulation of human alternative splicing by the spliceosomal small nuclear RNAs
Heidi Dvinge, Robert Bradley
12:55-01:15pmAwards and Closing remarks

Hayes Ballroom CDE

01:30-02:45pmCareer Mentoring lunch

Hayes Ballroom B