Agenda
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Friday, Oct 24
| Time | Event |
|---|---|
| 09:00-12:00pm | Optional Workshops 1 and 2 (registration required) |
| 01:00-01:15pm | Welcome and Introductory remarks |
Session I: Session 1: Translational Control & Disease Mechanisms | |
| 01:15-01:30pm | Ribosome association excludes stress-induced gene mRNAs from stress granules Noah Helton, Ben Dodd, Stephanie Moon Department of Human Genetics, University of Michigan |
| 01:30-01:45pm | Translational control of a unique bicistronic gene linked to Prader-Willi syndrome Lucia Johnson, Gemma May, Robert D Nicholls, Joel McManus Biological Sciences, Carnegie Mellon University |
| 01:45-02:00pm | Systematic analysis of ribosome recruitment to trinucleotide repeats Audrey Hoelscher, Ben Pockrass, Jacob Horn, Leidy Vanegas Cano, Sinem Ovunc, Peter Todd, Rachel Niederer University of Michigan, Department of Biological Chemistry |
| 02:00-02:15pm | Mechanisms of the RNA Topoisomerase 3B in translational control and neurological disease Julia E. Warrick, Durga Attili, Sami J. Barmada, Benjamin Pastore, Wen Tang, Michael G. Kearse Department of Biological Chemistry and Pharmacology, Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA |
| 02:15-02:30pm | Identification of TP53-independent stress responses in eukaryotic models of Shwachman-Diamond syndrome Noah Saito, Neha Prasad, Masayo Fujiwara, Julie Fox, Joseph Luna, Seth Corey Case Western Reserve University |
| 02:30-02:45pm | Loss of function of RNA-binding protein PRRC2B causes translation dysregulation and congenital heart defects Aleksandr Ivanov, Debojyoti Das, EngSoon Khor, Feng Jiang, Jiali He, Yui Kawakami, Peng Yao Aab Cardiovascular Research Institute, School of Medicine and Dentistry, University of Rochester |
| 02:45-03:15pm | Coffee break |
| 02:45-03:15pm | PI Meeting |
Session II: Session 2: RNA Modifications & Small RNA Regulatory Systems | |
| 03:15-03:30pm | Unexpected Parallels Between Archaeal and Eukaryotic Modifications Catalyzed by the SPOUT Family tRNA Methyltransferase 10 Catherine B. Whitney, Jesse Leavitt, Alexander Alon, Thomas Santangelo, Todd Lowe, Jane E. Jackman The Ohio State University, Department of Chemistry and Biochemistry and Center for RNA Biology |
| 03:30-03:45pm | The Influence on Translation and Biological Affects by the tRNA Methytransferase 1 (TRMT1) Chenghong Deng, Dr. Kejia Zhang, Xinyu Wang, Grace Yang, Helen Jackson, Jiaming Mao, Dr. Dragony Fu University of Rochester |
| 03:45-04:00pm | Dihydrouridine modification in tRNA impact ribosome frame maintenance during protein synthesis Chathuri Pathirage, Kaley Simcox, Maddy Zamecnik, Xingchen Liu, Lauren Barnes, Yubin Kim, Kristin S. Koutmou Department of Chemistry, University of Michigan |
| 04:00-04:15pm | Neurodevelopmental disorder-linked Argonaute mutations permit incorrect miRNA loading Andrew Savidge, Huaqun Zhang, Vishal Adhav, Geunyoung Sim, Audrey Kehling, Zhangfei Shen, Tianmin Fu, Kotaro Nakanishi Dept. of Chemistry and Biochemistry, The Ohio State University |
| 04:15-04:30pm | Designing cityRNAs targeting single-nucleotide KRAS mutations Mackenzie Dillenbeck, Audrey Kehling, Huaqun Zhang, Kotaro Nakanishi Department of Chemistry and Biochemistry, The Ohio State University |
| 04:30-04:45pm | Title not published online - please see booklet Marjia A., Farheen N., Prem K. and Lovlesh T., Amit G., Jillian G., Bibo L. Cleveland State University, Center for Gene Regulation in Health and Disease, Department of Biological, Geological, and Environmental Sciences, College of Arts and Sciences, Cleveland, OH |
| 04:45-05:00pm | Brief Break |
Session III: Keynote Lecture | |
| 05:00-06:00pm | Co-transcriptional RNA processing enables RNA to be a first responder Karla Neugebauer Molecular Biophysics and Biochemistry, Yale University |
| 06:00-08:00pm | Dinner |
| 08:00-09:30pm | EVEN Posters |
| 08:00-11:00pm | Poster Session and Reception |
| 09:30-11:00pm | ODD Posters |
Saturday, Oct 25
| Time | Event |
|---|---|
| 07:00-08:30am | Breakfast |
Session IV: Session 3: RNA Structure, Folding, & Biophysics | |
| 08:30-08:45am | Going in circles, staying in control: How circRNA helps bacteria weather stress Avleen K. Chawla, Mary J. Billings, Anna M. Kietrys Carnegie Mellon University |
| 08:45-09:00am | Title not published online - please see booklet Rajesh Kumar Reddy Sannapuredi, Yaping Liu, Rafael Davish, Sydney Steele, Bruce A. Johnson, Sarah Keane Biophysics and University of Michigan |
| 09:00-09:15am | Detection of pUG Fold Quadruplexes in Human Cells Mohsen Badiee, Samuel E. Butcher Biochemistry, University Wisconsin-Madison |
| 09:15-09:30am | Fine scale structural information substantially improves multivariate regression model for mRNA in-vial degradation prediction Soon Yi, Sara E Ali, Yashrajsinh Jadeja, J. Wade Davis, Mihir Metkar Department of Biochemistry, Case Western Rserve University School of Medicine |
| 09:30-09:45am | Biochemical mechanism of SARS-CoV-2 nucleocapsid protein phosphorylation-induced functional switch Megan S. Sullivan, Michael Morse, Kaylee Grabarkewitz, Dina Bayachou, Ioulia Rouzina, Vicki Wysocki, Mark C. Williams, Karin Musier-Forsyth Chemistry and Biochemistry, Center for RNA Biology, Center for Retroviral Research, The Ohio State University |
| 09:45-10:00am | A large and ancient bacterial noncoding RNA enables adaptation to various stresses Seth E. Lyon, Chrishan M. Fernando, Freya D. R. Wencker, Hannah Barsouk, Ronald R. Breaker Molecular Biophysics & Biochemistry, Yale University |
| 10:00-10:30am | Coffee break |
Session V: Session 4: RNA-Protein Complexes & Gene Regulation | |
| 10:30-10:45am | RNA-binding proteins activate transcription through defined molecular grammars Dervla Moore-Frederick, Haoran Wang, Lydia Phillips, Bailey Webster, Deyuan Xu, Arth Banka, Grant Mowry, Emily Wang, Sid Srivastava, Jonathan E Henninger Department of Biological Sciences, Carnegie Mellon University |
| 10:45-11:00am | Towards a Model of RNA Regulation by Fatty Acid Synthase Yelena Perevalova, Marcin Sajek, Byungil Kim, Neelanjan Mukherjee, Manuel Ascano Department of Biochemistry, Vanderbilt University |
| 11:00-11:15am | Measuring the Transcriptional and Splicing Effects of Optically Activated IRE1 and the Unfolded Protein Response Jacob W. Smith, Vladislav Belyy Department of Chemistry and Biochemistry, The Ohio State University |
| 11:15-11:30am | Dissecting unexpected connections between transcriptional control and Nonsense Mediated mRNA Decay Rene Arvola, Toby Frazer, Debadrita Paul, Ryan Denniston, Michael Schiff, Ralf Bundschuh, Sharon Amacher, Guramrit Singh Department of Molecular Genetics, The Ohio State University |
| 11:30-11:45am | Genetically encoded chemical crosslinking of RNA (GECX-RNA) for enhanced CRISPR/Cas applications Pabina Pokharel, Wei Sun Department of Biochemistry, Virginia Tech |
| 11:45-12:00pm | Riboregulation of an innate immune signaling complex Nandan Gokhale Division of Immunobiology, CCHMC |
| 12:00-12:30pm | Awards and Closing Remarks |