Talk abstracts

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Time Presenter Title PI
Friday 01:30-01:45pmCatherine Douds
 A novel reagent for mutational profiling of RNA in vivo Phil Bevilacqua
Saturday 11:45-12:00pmLingzi Hong
 Act1 propels chemoresistance by modulating redox homeostasis via epitranscriptomic regulation of antioxidant RNA metabolism Xiao Li
Friday 02:30-02:45pmCatherine Wilhelm
 Bacterial RNA-free RNase P: structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P Markos Koutmos
Saturday 12:15-12:35pmAnna M. Kietrys
 Circular RNAs: an underdog of HIV diagnostics Anna M. Kietrys
Saturday 09:00-09:15amMike Holmes
 Depletion of eIF4E1 drives Toxoplasma gondii parasite stage differentiation and latency Bill Sullivan
Friday 01:15-01:30pmJerricho Tipo
 Dual conformational states of HIV-1 RRE stem-loop II and implications for the initial high-affinity Rev interaction Choi, Kay
Saturday 08:45-09:00amAkila Venkataramany
 Examining the therapeutic effects of splice-switching oligonucleotides for insulin receptor in osteosarcoma. Dawn Chandler
Friday 01:45-02:00pmMika Schievelbein
 Global RNA modifications to the MALAT1 triple helix affect thermostability and weaken binding to METTL16 Jessica Brown
Friday 04:15-04:30pmKailey Worner
 Identification of RNA-binding proteins’ direct effects on gene expression via the degradation tag system Wenqian Hu
Saturday 11:15-11:30amKristen Nedza
 Investigating the interactome and functions of the UPF3 paralogs in Nonsense Mediated Decay Guramrit Singh
Friday 04:00-04:15pmElizabeth Franklin
 Ligand and transcription factor NusA differentially modulate 30S subunit recruitment by a translational riboswitch-controlled mRNA Nils Walter
Saturday 11:30-11:45amYou Jin Song
 Long non-coding RNA MALAT1 regulates hypoxia-responsive alternative splicing by acting as a RNA-binding protein scaffold Prasanth Kannanganattu
Saturday 10:30-10:45amMax Baymiller
 Loss of tRNA synthetase activity breaks an RNA cycle during stress Stephanie Moon
Friday 03:30-03:45pmRajeev Yadav
 Mechanics of divalent ion sensitivity of the manganese-sensing riboswitch measured by combined high-resolution optical tweezers and single-molecule fluorescence Matthew J Comstock
Friday 03:15-03:30pmOshadhi Jayasinghe
 NusG-dependent RNA polymerase pausing is a common component of riboswitch regulatory mechanisms Paul Babitzke
Saturday 09:30-09:45amPavithra Madamarandawala
 Parkinson's Disease associated genes are directly regulated by Pumilio proteins Wendy Olivas
Saturday 11:00-11:15amZhiyan Silvia Liu
 PARP1 inhibition at R loops selectively kills spliceosome mutant leukemias by triggering transcription-replication conflicts. Hai Dang Nguyen
Saturday 12:00-12:15pmMinli Ruan
 Pseudouridine Synthase 7 localization influences mRNA modification landscape and stress tolerance Kristin Koutmou
Friday 02:15-02:30pmTharun Selvam Mahendran
 RNA-driven Percolation Transitions in Aging Biomolecular Condensates Priya Banerjee
Saturday 10:45-11:00amSepideh Fakhretaha Aval
 Role of the sarcin-ricin loop (SRL) of 23S rRNA in assembly of the 50S ribosomal subunit Kurt Fredrick
Saturday 09:15-09:30amXiang Liu
 Small Circular mRNA Vaccines for Tumor Immunotherapy Dr. Guizhi Zhu
Saturday 12:35-12:55pmScott Aoki
 Structural biology paired with in silico screening to predict RNA modification-protein interactions Scott Aoki
Saturday 09:45-10:00amMichael Owens
 The cellular morphologies of cancer-related DDX3X mutants are defined by their catalytic activities Kathy Fange Liu
Friday 02:00-02:15pmJoe Kanlong
 The role of transcriptional start site heterogeneity in the translation of HIV-1 genomic RNA Karin Musier-Forsyth
Friday 03:45-04:00pmJingyi Liu
 Unraveling Cell-Type-Specific Alternative Cleavage and Polyadenylation Regulatory Mechanisms Governed by CLP1 Ashleigh Schaffer