Poster abstracts

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Number Presenter Title PI
1Lauren Barnes
A Comparison of RNA Sequencing by Conventional and Nano Liquid Chromatography Tandem Mass Spectrometry Methods Kristin Koutmou
2Lo Sosinski
A model for recognition events in non-coding RNA structures Charles Hoogstraten
3Kaizheng Liu
A New "On/Off Switch" for RNA: Reversible Acylation Responsive to Esterases Anna M. Kietrys
4Tetyana Lukash
A novel micropeptide suppresses translation of the stress response factor ATF4 Deepika Vasudevan
5Sonia Ling
A pipeline for Bisulfite Pseudouridine Detection (B-PsiD) Chase Weidmann
6Jocelyn Chen
A regulatory RNA:RNA interaction between a SAM-I riboswitch and RNA thermosensor in Listeria monocytogenes Sarah Keane
7Teresa Wolak
A Systematic Approach to Ribosome-Targeting using the Antimicrobial Peptide Oncocin Christine Chow
8Jacob Horn
A thorough investigation of SARS-CoV-2 5’ UTR elements that regulate viral translation. Rachel Niederer
9Grace Eramo
Alternative splicing in the 5` untranslated region of mRNA as a mechanism of translational control Rachel Niederer
10Ben Pockrass
An element in the CFTR 5' UTR represses ribosome recruitment and translation Rachel Niederer
11Taylor Opolka
An Unexpected Branch in the Family Tree: Biochemical Investigation of Novel Branching Ligase Ribozymes Saurja DasGupta
12Sulayman Ahmed
Analysis of the Agaricus bisporus (mushroom) OAZ RNA using Dual Luciferase Assays (DLA) Juliane Soukup
13Erin Prestwich
Analysis of tRNA modifications in fibroblasts and myofibroblasts after arsenite exposure Erin Prestwich
14Aastha Gyawali
Assessing RNA stability in ionic liquids Pat Limbach
15Kobie Kirven
Title not published online Phil Bevilacqua
16Alessandra Kakish
Bacterial growth in the presence of glms riboswitch analogs Juliane Soukup
17Ling Chen
Binding of Bacillus subtilis cold shock protein CspB with RNA and DNA Phil Bevilacqua
18Lipika Baidya
Bridging of Ions Induces Structural Switch in the Conformational Ensemble of Poly(ADP-Ribose) (PAR) Hung T Nguyen
19Liuqing Yang
Cardiomyocyte-Specific Loss of eIF4G2 Disrupts Translational Homeostasis and Triggers Progressive Cardiac Remodeling and Late-onset Heart Failure Peng Yao
20Jayod Kariyawasam
Challenging the Cationic Paradigm: Structural and Functional Studies of Oncocin–Ribosome Interactions Christine Chow
21Rabab Abu Alhasan
Characterization of a large NMD complex that accumulates upon loss of UPF3 factors in human cells Guramrit Singh
22Erica Popa
Characterization of RNase P RNAs in bacterial prophages Venkat Gopalan
23Dr. Lei Pan
Characterization of TGFβ-inducible global-proteomic and phosphor-proteomic changes in activated immortalized human cardiac fibroblasts Peng Yao
24Martin OSteen
Characterization of the prfA RNA Thermosensor Sarah Keane
25Zoe Limberopoulos
Characterizing the 3' Cleavage Activity of Aquifex aeolicus RNase P Homologs on pre-tRNA Substrates Markos Koutmos
26Jade Hostetler
Characterizing the Functions of LncRNAs in Retina Development Brian Clark
27Marrett Gilfus
Chemical Crosslinking Strategies for RNA Wei Sun
28Anwesha Ghosh
Title not published online Phil Bevilacqua
29My Le
Circularization of DENV genome in regulating replication of the virus Kay Choi
30Diego A Rosado-Tristani
CisBP-RNA: A database of sequence specific RNA-Binding Protein motifs Matthew Weirauch
31Shaokun Li
CLP1 R140H mutation disrupts alternative polyadenylation in a neurodegenerative disorder - PCH10 Ashleigh Schaffer
32Mohammad Lutful Kabir
Combined CRISPR-activation and CRISPR-interference capabilities using dCas and G-quadruplex Structures Hamza Balci
33Alfa Dhakal
Combined loss of ADARs and RDE-4 provides resistance to an opportunistic human pathogen Heather Hundley
34Annastasia Minor
Title not published online Wenqian Hu
35Danielle Wampler
Computational modelling of RNA-protein binding interactions under an external force Ralf Bundschuh
36Anuprova Bhowmik
Computational Pathology Analysis Links ESRP2 Dysregulation to Injury Patterns in MetALD Auinash Kalsotra
37Chathurani Ekanayake
Contrasting recognition mechanisms exists for m⁵C located withing different RNA sequences Sanjaya Abeysirigunawardena
38Annabelle Elsner Pacheco
Correction of multiple splicing mutations associated with CFTR exon 18 using a single exon specific U1 snRNA (ExSpeU1) Hua Lou
39Julia Haas
Covalently Targeting Conserved Cysteines in RNA Binding Domains Brittany Morgan
40Monica Pillon
CryoEM structure of the SLFN14 endoribonuclease reveals insight into RNA binding and cleavage Monica Pillon
41Jennifer Bennett
Cyclic di-GMP control of developmental genes in Streptomyces coelicolor Jennifer Bennett
42Minli Ruan
Cytoplasmic localization of PUS7 facilitates a pseudouridine-dependent enhancement of cellular stress tolerance Kristin Koutmou
43Alexander Chen
Deciphering Function and Mechanism of eIF4G2 in mRNA Translation Regulation in Cardiomyocytes: Insights into Cardiac Health and Disease Peng Yao
44Jiali He
Deciphering the function and mechanisms of translation elongation factor eIF5A in cardiomyocytes under heart disease Peng Yao
45Leanne Kelley
Defining the spatiotemporal impacts of DEAD-box helicases on RNA editing Heather Hundley
46Junxing Chen
Title not published online Wei Sun
47Chin Wang
Determining the function of human TDRD7 in RNA granule formation Wen Tang
48Md Bappy Hawlader
Title not published online Pat Limbach
49Chinedum Udekwu
Title not published online Olorunseun Ogunwobi
50Thaanya Amarasekara
Discovering the hidden potential of 3'-5' polymerases: substrate specificities of Thg1-like proteins Jane Jackman
51Jacob Schwartz
Discriminant silencing of pathogenic AGO1 mutants using cityRNAs Kotaro Nakanishi
52Anthony Caputo
Disruption of CLP1 alters neuronal lineage specification and alternative polyadenylation landscapes in human cortical organoids Ashleigh Schaffer
53Caroline Rodrigues
Dissecting CAG Repeat Length-Dependent Transcriptional and Functional Alterations in SBMA Using Human iPSC-Derived Neuromuscular Models Helen Miranda
54Swapnil Mukherjee
Dissecting the mechanism of IRE1 activation with orthogonal control over oligomerization and phosphorylation Vladislav Belyy
55Arnab Roy
Downregulation of ESRP2 and RNA mis-splicing leads to MetALD-associated liver pathophysiology Auinash Kalsotra
56Jessica Derham
Dynamic expression of a splicing factor promotes cell migration and proliferation following drug-induced, acute liver injury Auinash Kalsotra
57Rohan Krishna
Title not published online Joseph Luna
58Debojyoti Das
eIF4G2: A crucial player in pathological tissue fibrosis and a potential therapeutic target Peng Yao
59Rosella Stower
Elucidating the mechanism of Trm4 mediated gene regulation Kristin Koutmou
60Shashi Singh
Engineered circ-arRNAs enable RNA editing and splice modulation for tunable oncogene silencing Joseph Luna
61Henry Arthur
Engineering circular guide RNAs for Type I CRISPR mediated gene editing in human cells Yan Zhang
62Neha Deshpande
Enzymatic synthesis of ITP-incorporated RNA for NMR-based structural investigations Sarah Keane
63James Londino
Examining the Role of Transfer RNA in the Response to Infection James Londino
64Khondakar Sayef Ahammed
EXOSC1/Csl4 exosomopathy variants have distinct and overlapping in vivo effects on budding yeast RNA exosome function Ambro van Hoof
65Boyoon Yang
Exploring the importance of sequence-specific dsRNA recognition of ADARs in vivo Heather Hundley
66Belal Chowdhury
Exploring the interplay between translational control and alternative splicing using multi-omics analyses of a neurohumoral-induced cardiac hypertrophy mouse model Peng Yao
67Hannah Hertz
Exploring the properties of RNA polymerase II condensates at the splicing leader cluster Wen Tang
68Moulisubhro Datta
Exploring the role of a tRNA SNP in the molecular basis of dextrocardia, a laterality disorder Venkat Gopalan
69Caitlin Schroeder
From structure to function: how 7S RNA shapes mitochondrial transcription Alfredo Hernandez
70Hen Gelshtein
G•U wobble pair within an RNA identified by structural informatics as a candidate for alternative protonation states Phil Bevilacqua
71Rachel Morris
Guardians of nutrient flow: transcriptomic insights into transporter interference in the tsetse–Wigglesworthia symbiosis Rita Rio
72Dibyajyoti Mohanta
Heterogeneous Aging of RNA Condensates Hung T Nguyen
73Amanda Panfil
HTLV-1 infection reshapes cellular m6A RNA modifications Amanda Panfil
74James Roll
Identification of 3D motifs in Rfam with JAR3D Roll James
75Xiaoyan Li
Identifying the mechanism of PUS7 relocalization upon stress Kristin Koutmou
76Janan Alfehaid
Impact of Small Molecules on Telomeric Overhang Accessibility Hamza Balci
77Maddy Zamecnik
Incorporating common ASO modifications into mRNAs impacts translation speed Kristin Koutmou
78Bojing Zhu
Integrated Profiling of tRNA Modifications in the Cystic Fibrosis Cell Model with PTC suspression Kristin Koutmou
79Marla Gravino
Into the Unknown: Covalently Targeting RNA with Electrophilic Warheads Brittany Morgan
80Sakinah Owens
Investigating 40S Scanning of 5' UTRs to Detect Enrichment of mRNAs Rachel Niederer
81Sarah Fowler
Investigating a potential eukaryotic riboswitch in OAZ RNA from Agaricus bisporus via in-line probing Juliane Soukup
82Dana Beseiso
Investigating alternative Transcription Start Site (TSS) usage in breast cancer Rachel Niederer
83Aaron Clarke
Title not published online Sara Zimmer
84Antigone Wilson
Investigating structural and functional elements critical for complex formation between the SreA riboswitch and prfA thermosensor Sarah Keane
85Toby Frazer
Investigating the effect of UPF3 disease-linked mutations on nonsense-mediated mRNA decay Guramrit Singh
86Rachel Robertson
Investigating the folding and dynamics of a tRNAArgUCU isodecoder associated with neurodegeneration Venkat Gopalan
87Sydney Steele
Investigating the molecular determinants of pri-miR-20a binding by the tandem RRMs of hnRNP A2/B1 Sarah Keane
88Annie Urban
Investigating the role of bS21 paralogs in Agrobacterium fabrum Kurt Fredrick
89Taha Alubaidi
Investigating the Role of Glycerol and Glycerol-3-Phosphate on RNA Stability Phil Bevilacqua
90Emma Lamb
Title not published online Heather Hundley
91Clare Austin
Investigating the role of P-bodies in Pnrc2-mediated oscillatory transcript decay Sharon Amacher
92Leidy Johana Vanegas Cano
Investigating the role of ribosomal RNA pseudouridylation in regulating translation Rachel Niederer
93Michael Brandt
Investigating the role of sequestration of the 3' tail of the 16S rRNA in ribosomes of Flavobacterium johnsoniae Kurt Fredrick
94Abigail Kelly
Investigating tRNA maturation by Protein-Only RNase P (PRORP) & the Elucidating the Role of Interacting Methyltransferases in Arabidopsis thaliana Markos Koutmos
95Chamali Thalagaha Mudiyanselage
Investigation of the impact of m6A nucleotide modification on FUS-dependent biological liquid-liquid phase separation Sanjaya Abeysirigunawardena
96Olivia Roumaya
Investigation of vertebrate tRNA methyltransferases Trmt10a and Trmt10b in zebrafish Jane Jackman
97Peter Zhang
Ion-dependent structural ensemble and phase separation propensity of single-stranded RNA Hung Nguyen
98Junnan Fang
Isoform expression and post-transcriptional regulation of centrosomal Plp mRNA Junnan Fang
99Daniel Corey
Kinetic and cryoEM studies into bacterial protein only RNase Ps Markos Koutmos
100Yui Kawakami
Loss of EIF5A Disrupts Cardiac and Skeletal Muscle Proteostasis and Causes Early onset Cardiomyopathy and Lethality Peng Yao
101Ashwini Shivakumar
Male-specific gene expression during seed development enables early sex identification in Cannabis sativa L. Arthur Hunt
102Debadrita Paul
Measurement of mRNA decay kinetics to investigate contributions of factor specificity and transcriptional regulation to NMD Guramrit Singh
103Alana Weaver
Measuring the Binding Affinity of the Trans-Editing Enzyme, ProXp-x, to Deacylated Bacterial tRNAs Lexie Kuzmishin Nagy
104Vy Nguyen
Measuring the Effect of D-Ala vs. L-Ala on E. coli Lacking their Inherent D-Amino Acid Defense Enzyme Lexie Kuzmishin Nagy
105Brandon Michalides
Mechanistic characterization of RNA-dependent interactors of the MAVS signalosome Nandan Gokhale
106Chloe Nagasawa
Micromanaging the Message: Distinct roles of miR-29 family members in MDM2 splicing and tumor stress response Dawn Chandler
107Samarth Kumar
Mitochondrial antiviral-signaling protein (MAVS) LLPS is promoted by cellular RNA Nandan Gokhale
108Amelia Pfaff
Modeling TARDBP-Associated ALS Using iPSC-Derived Neuromuscular Junctions for Mechanistic and Therapeutic Discovery Helen Miranda
109Xia Zhou
Modulation of Insulin Receptor Splicing in Hepatocellular Carcinoma: Mechanism and Therapy Dawn Chandler
110Aatiqa Nawaz
Title not published online Stephanie Ceman
111Hina Zain
Multiple endonucleases for digestion of tRNA anticodon regions to conduct modification mapping by LC-MS/MS Pat Limbach
112Alexa Schnell
Non-invasive cellular extraction of RNA (NICER-seq) for continuous monitoring of live cell states Joseph Luna
113Hailey Mulvihill
Novel small molecule screening of CAG expansion clonal inducible cell lines Kunal Chatterjee
114Jennifer Kist
Title not published online Pat Limbach
115Daniel Cline
Optimization of a high-throughput FRET assay for identification of potential antibiotic compounds Juliane Soukup
116Steven Nguyen
Optimization of a high-throughput FRET assay to study glmS riboswitch self-cleavage in Staphylococcus aureus Juliane Soukup
117Bibek Hamal
Optimization of RNase MC1 and Cusativin Digestion Protocols for tRNA Modification Mapping using LC-MS/MS Pat Limbach
118Vidusha Kothwela
Orthogonal Organic Phase Separation (OOPS) Reveals Virus-Specific RNA binding of Non-Canonical RNA-Binding Proteins During ZIKV and HCV Infections Joseph Luna
119Isabelle Juhler
PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer Kyle Cottrell
120Ye Zhou
Plp Isoform Expression and Function in Drosophila Neurodevelopment Junnan Fang
121Sandip Chorghade
Posttranscriptional Silencing of Poly A Binding Nuclear Protein 1 (PABPN1) in Cardiomyocytes Regulates Heart Development and Disease Progression Auinash Kalsotra
122Myles Thornton-Sherman
Title not published online Phil Bevilacqua
123Jae Bucknor
Probing the Mechanism of NRF2 Co-Activated lncRNA NMRAL2P in NSCLC Chase Weidmann
124Tasnin Nila
Probing the secondary structure of KIF5A pre-mRNA in wild-type and disease-associated mutants Karin Musier-Forsyth
125Pooja Madan Mohan
Protein Recoding Through mRNA Editing by tRNA Deaminases Yi Zhang
126Amelia Cochran
Pseudouridine synthase 4 exhibits a broad substrate scope in vitro Markos Koutmos
127Rachel Giles
Purine mRNA modifications impact translation speed Kristin Koutmou
128David Muzyka
Quantitative analysis of PUS enzymatic activity via Triple Quad Mass Spectrometry Kristin Koutmou
129Elizabeth Hout
Title not published online Sanjaya Abeysirigunawardena
130Subhashis Natua
Regulated intron retention directs the timely usage of transcripts during cardiac maturation and disease Auinash Kalsotra
131Christopher Bonar
Title not published online Patricia Clark
132Whitney Jimenez
Regulation of MDM2 Alternative Splicing by RNA-Binding Proteins and Conserved Cis-Elements Dawn Chandler
133Mahmuda Akter
Ribosome heterogeneity impacts stable RNA homeostasis and enables phenotypic variation in Escherichia coli Kurt Fredrick
134Yichen He
RNA dynamics in artificial cytoplasm Phil Bevilacqua
135Kaitlin Klotz
RNA ensembles at work: molecular and structural determinants of telomerase function in a human parasite Kausik Chakrabarti
136Isabel Thompson
RNA hairpin folding with unbiased weighted ensemble sampling Steve Corcelli
137Aftab Mollah
RNAs with UAG sequence and m6A nucleotide modifications bind cooperatively to hnRNP A1 Sanjaya Abeysirigunawardena
138Brendan Moran
Role of LOTUS domain and DEAD-box proteins in condensate assembly and small RNA production Wen Tang
139Andy Briercheck
Role of rRNA Methyltransferases During Bacterial Cold Shock Adaptation Yan Zhang
140Zixi Long
Role of YBX1 in the HTLV-1 Lifecycle Karin Musier-Forsyth
141Danni Li
Roles of FRMP in the post-transcriptional regulation of centrosomal Plp mRNA Junnan Fang
142Brendan Pew
Title not published online Wen Tang
143Hamza Balci
Single Molecule Investigations on Accessibility of Long Telomeric Overhangs Hamza Balci
144Anna Childers
SRPK1 interacts with the HTLV-1 hbz RNA and influences cellular proliferation Amanda Panfil
145Shawn Ramachandran
Structural analysis of OAZ RNA from Homo sapiens Juliane Soukup
146Fiona Tillyer
Structural and Enzymatic Characterization of PUS4 Homologs Markos Koutmos
147Ross Kaufhold
Structural basis for repeat-associated non-AUG translation initiation on C9orf72 RNA Jailson Brito Querido
148Brenna Saladin
Structural basis of ribosomal hibernation across eukaryotes Brito Querido
149Suada Leskaj
Structural characterization of translation initiation on HPV-18 E6 mRNA Jailson Brito Querido
150Kaushani Misra
Studying modifications in a brain-enriched tRNA isodecoder Dragony Fu
151Kira Holton
Substrate recognition and functional consequences of the mRNA modifying enzyme PUS7 Chase Weidmann
152Grace Johnecheck
Substrate Recognition by Two 3' to 5' RNA Polymerases in Dictyostelium discoideum Jane Jackman
153Brandon Iwaniec
Surveying tRNA introns across the eukaryotic tree: The intron in tRNATyr-GUA is almost universal, but some species lack all tRNA introns Ambro van Hoof
154Sophie Rodionova
Synthesis and Assembly of RNA Nanoparticles for Prostate Cancer Diagnostic Emil Khisamutdinov
155Helen Washington
Targeting the NLRP3 inflammasome with antisense oligonucleotides as a therapeutic approach in psoriasis Michelle Hastings
156Fawwaz Naeem
The anti-Shine-Dalgarno element of 16S rRNA is needed for translation of one gene, rpsU, in Flavobacterium johnsoniae Kurt Fredrick
157Adam Wier
The AUGCs: Learning the chemistry of RNA through a mass-spectrometry screen of electrophiles Brittany Morgan
158Sarah Liu
The Belle dependent post-transcriptional regulation of centrosomal genes Fang Junnan
159Geqi Li
The role of the Nop2 N-terminal IDR in yeast ribosome biogenesis John Woolford
160Emily Slobodenyuk
Three genes, one protein: Investigating 3'UTR-driven mRNA localization and protein function of the calmodulin gene family Chase Weidmann
161Swetha Subramanian
Timed PABPN1 silencing orchestrates mRNA 3′-end remodeling to drive cardiac maturation Auinash Kalsotra
162Alice Youle
Translation of CFTR Proceeds from Multiple Start Sites Rachel Niederer
163Jiaming Mao
TRMT1 affects mitochondria function Dragony Fu
164Neil White
Uncovering Elemental Ion Biology with Riboswitches Neil White
165Kayla Lenshoek
Uncovering how lncRNA MALAT1 controls gene expression in cancer metastasis Chase Weidmann
166Mara Reynolds
Understanding the impact of 5-fluorouracil on tRNA in Saccharomyces cerevisiae Jane Jackman
167Kate Desrochers
Understanding the Modification Landscape of Anticodon-Engineered tRNAs and their Implications for Cystic Fibrosis Treatment Kristin Koutmou
168Annyesha Biswas
Title not published online Saurja DasGupta
169Lizette Zavala
Unraveling the biochemical characteristics of target of EGR1 (TOE1) linked to pontocerebellar hypoplasia Cassandra Hayne
170Sarah Nock
UPF1 binding to neo-UTRs marks aberrant transcripts for nonsense-mediated mRNA decay in yeast Kristian Baker
171Uday K. Baliga
Upstream open reading frame inactivation augments GATA4 translation and cardiomyocyte hypertrophy in mice Peng Yao
172Megan Westwood
Use of steric blocking antisense oligonucleotides for the targeted inhibition of junction-containing precursor miRNAs Sarah Keane
173Anasemon Botros
Using Antisense Oligonucleotides to Induce Exon 10 Skipping as a Potential Therapeutic Treatment for Spinocerebellar Ataxia Type 3 (SCA3) Mallory Havens
174Cassandra Smoak
Validation of ZYS-1 as an ADAR1 inhibitor Kyle Cottrell
175Sebastian Urbano
When a DNA helicase meets RNA: Twinkle at the replication fork and beyond! Alfredo Hernandez
176Oliver Marchus
x1 encodes a putative RNA-binding protein required for paramutation Jay B. Hollick