Poster abstracts
Poster number 139 submitted by Meher Akhlas Nuri
Aptamer-powered surveillance of SARS-CoV-3
Jacob Eicholtz (Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University), Ryanna Tuttle (Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University), Dylan Hohlfelder (Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University), Satya Prakash Arya (Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University), Andrew Manazer (Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University), Xiaohong Tan (Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University)
Abstract:
Rapid detection of emerging coronaviruses is critical for preparedness. The S2A2C1 aptamer broadly recognizes Beta-coronavirus S2 domains but not influenza proteins. A sandwich aptamer assay achieved ∼0.51 pM detection limits and functions in serum, enabling a sensitive, adaptable platform for universal coronavirus detection and real-time surveillance of emerging variants.
Keywords: Sandwich Aptamer, Coronavirus Detector