Talk abstracts

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Time Presenter Title PI
Friday 01:15-01:30pmAnthony Caputo
 T-sncR-seq allows for robust detection of transfer RNAs and other small noncoding RNAs at single cell resolution Ashleigh Schaffer
Friday 01:30-01:45pmElizaveta Karchuganova
 Structure, binding and activity of the human tRNA modification enzyme TRIT1 with tRNA-Sec Markos Koutmos
Friday 01:45-02:00pmThaanya Amarasekara
 Discovering the hidden potential of 3-5 polymerases: high-throughput substrate specificities of Thg1-like proteins Jane Jackman
Friday 02:00-02:15pmDanielle Wampler
 Computational modeling illuminates structural changes caused by a neurodegeneration-associated C50U mutation in a tRNA-Arg-UCU isodecoder Ralf Bundschuh
Friday 02:15-02:30pmLizette Zavala
 Substrate recognition and catalysis by TOE1: biochemical and structural insights into snRNA 3-end maturation Cassandra Hayne
Friday 02:30-02:45pmChanJuan Dong
 Cellular signal-responsive m5C editing by an inducible split CRISPR platform Fu-Sen Liang
Friday 03:15-03:30pmShyama Nandakumar
 A uORF-encoded micropeptide provides evolutionarily conserved control of stress-responsive translation Deepika Vasudevan
Friday 03:30-03:45pmBrenna Saladin
 Structural basis for repeat-associated non-AUG translation initiation on C9orf72 mRNA Jailson Brito Querido
Friday 03:45-04:00pmAlice Youle
 High-throughput discovery of 5UTR structures that regulate translation Rachel Niederer
Friday 04:00-04:15pmArtem Astafev
 Caloric restriction reprograms circadian rhythms in global and selective protein translation. Roman Kondratov
Friday 04:15-04:30pmBrendan Moran
 Spatially localized activation of an RNA helicase facilitates siRNA biogenesis within a phase-separated condensate Wen Tang
Friday 04:30-04:45pmVishal Adhav
 Structural basis for microRNA-length maintenance Kotaro Nakanishi
Friday 05:00-06:00pmAlan Hinnebusch
 Decoding Translational Reprogramming: Direct and Indirect Molecular Programs Shaping Eukaryotic Gene Expression Alan Hinnebusch
Saturday 08:30-08:45amHaoran Wang
 RNA-binding proteins activate transcription through defined molecular grammars Jonathan Henninger
Saturday 08:45-09:00amMorgan Shine
 Gradual and sudden heat exposure induce distinct alternative splicing programs in green algae Karla Neugebauer
Saturday 09:00-09:15amBailey Webster
 Synthetic assembly of transcriptional condensates by RNA-binding proteins Jonathan Henninger
Saturday 09:15-09:30amAnton Blatnik
 A novel SMN mutant implicates correction of UsnRNP biogenesis and pre-mRNA splicing as critically associated with suppression of SMA Mitchell Drumm
Saturday 09:30-09:45amIsa Ozdemir
 CHD7 regulates replication-dependent histone expression via altered 3 end mRNA processing Sarah Hainer
Saturday 09:45-10:00amBenjamin Fair
 Distinct U1 cofactor requirements link Branaplam and Risdiplam specificity to splice-site context Yang Li
Saturday 10:30-10:45amJacob Devos
 The iron-sensing czcD riboswitch and its associated protein drive cell viability and infection in Listeria monocytogenes Joey Cotruvo
Saturday 10:45-11:00amZiyao Zhu
 Engineering a Fluorogenic RNA Biosensor toward Selective Imaging of Flavin Adenine Dinucleotide in Living Cells DasGupta Saurja
Saturday 11:00-11:15amYi-Meng Lo
 Efficient Zero-footprint Intracellular RNA Labeling via URIL-Stem Replacement and Triplex-guided Covalent Crosslinking Dennis Bong
Saturday 11:15-11:30amHolly Shultz
 Mapping the Structure and Conformational Landscape of the 10-23 DNAzyme Aaron Robart
Saturday 11:30-11:45amElise Kelley
 Biophysical evidence for G-quadruplex/hairpin equilibrium in HIV-1 antisense RNA Karin Musier-Forsyth
Saturday 11:45-12:00pmYaqiang Wang
 Rules of engagement: how small molecules bind RNA in the SPIRAL database Yaqiang Wang