Poster abstracts

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Number Presenter Title PI
44Elise Dunshee
Functional dissection of intrinsically disordered N-terminal regions of human Pumilio proteins that repress gene expression Aaron Goldstrohm
147Dmitrii Travin
Manikomycin inhibits prokaryotic translation by targeting the E site of the large ribosomal subunit. Alexander Mankin
156Andrew Weeks
Zinc-dependent regulation of sod1 mRNA transcript levels. Amanda Bird
4Alexander Ahn
Alternative RNA Splicing in Skeletal Muscle from Exercise, Rapamycin, and Aging. Andrew Ludlow
77Jeongjin Kim
Discovery and characterization of a novel telomerase alternative splicing isoform that protects lung cancer cells from chemotherapy induced cell death Andrew Ludlow
134Paolo Sinopoli
tRNA introns act as novel noncoding regulatory RNAs Anita Hopper
119Ernesto Roldan-Bonet
Genome-wide application of a tRNA assay to uncover proteins involved in the tRNA retrograde pathway Anita Hopper
58Jackson Hastings
Identification of tRNA export adaptors in Saccharomyces cerevisiae Anita Hopper
95Matt McPherson
Studies to determine if tRNA retrograde nuclear import is an iterative process Anita Hopper
22Anna Blumental-Perry
MtDNA Encoded Non-coding RNA, mito-ncR-LDL805, Relocates to the Nucleus and Increases Mitochondrial Bioenergetics Anna Blumental-Perry
107Noa Perry
Nuclear Level of mtDNA Encoded Non-Coding RNA Regulates Mitochondrial Bioenergetics Anna Blumental-Perry
96Jeff Medley
Regulation of miRNA Strand Selection in Caenorhabditis elegans Anna Zinovyeva
21Anton Blatnik
Sm-mRNP: Sm-protein rings can assemble on more than snRNAs Arthur HM Burghes
142Hannah Talbot
Encoding, Decoding, and Rendering Information in DNA Nanoswitch Libraries Arun Richard Chandrasekaran
26Arun Richard Chandrasekaran
Title not published online Arun Richard Chandrasekaran
112Ishita Purwar
TGF-ß signaling mediates downregulation of ESRP2 in alcoholic liver disease hepatocytes Auinash Kalsotra
3Oluwafolajimi Adesanya
DM1 CUG repeat expression alters cardiac mitochondrial respiration and dynamics Auinash Kalsotra
28Sandip Chorghade
Postnatal Silencing of Nuclear Poly(A) Binding Protein (PABPN1) Regulates Cardiac Gene Expression and Function Auinash Kalsotra
169Zac Dewald
Myotonic Dystrophy type 1 alters ACC1 function and induces liver lipid accumulation Auinash Kalsotra
100Subhashis Natua
Temporal Control of Dynamic PABPN1 Expression Governs Cardiac Maturation and Adult Cardiac Function Auinash Kalsotra
37Diptatanu Das
Altered splicing program leads to functionally aberrant liver secretome during alcoholic liver disease Auinash Kalsotra
14Nicholas Baker
Title not published online Auinash Kalsotra
121Antara Roy
The role of ribosomal protein L13a-dependent GAIT pathway regulates macrophage polarization during bone marrow differentiation. Barsanjit Mazumder
118Arlin Rodriguez
Self-Assembly of DNA Nanostructures in Different Cations Chandrasekaran Arun
62Kira Holton
Cellular Context for mRNA Substrate Selection by Pseudouridine Synthase 7 (PUS7) Chase Weidmann
85Kayla Lenshoek
Title not published online Chase Weidmann
64Sun Jeong Im
Title not published online Christine Chow
160Teresa Wolak
RNA-targeting antibiotic peptides: a multi-pronged approach Christine Chow
106Jiaqi Pei
Coacervates serve as protocytoplasm to help protect prebiotic RNA from hydrolysis under wet-dry cycling conditions Christine Keating
86Lauren Levesque
Role of nTr-25, a tRNA-Arg-UCU isodecoder, in establishment of left-right asymmetry in mammals Cole Susan
5Nida Ajmal
Developing high throughput assay for studying beta cell function and Type 1 Diabetes drug discovery Craig S. Nunemaker
102Fnu Palwasha
Type 1 Diabetes therapeutic compound MSB-61: using RNA sequencing to identify the mechanism Craig S. Nunemaker
47Cristina Espinosa-Diez
Regulatory role of the lncRNA CASC15 in vascular remodeling and its implications for chronic kidney disease Cristina Espinosa-Diez
167Mingyi Zhu
DecoyFinder: Identification of Decoy Sequences in Sets of Homologous RNA Sequences David H. Mathews
72Anees Mohammed Keedakkatt Puthenpeedikak
Refinement of the Amber Force Field For RNA: Improving the Description of Non-Bonded Interactions David Mathews
129James Seuch
Title not published online David Mathews
66Whitney Jimenez
MDM2 alternative splicing is post-transcriptionally regulated by miRNA-29b: A novel pathway of MDM2 regulation Dawn Chandler
114Rafia Rahat
Stabilizing antisense oligos for therapeutic delivery by extracellular vesicles for the treatment of pediatric cancers Dawn Chandler
84Zac LaRocca-Stravalle
The Dichotomy of MDM2 Splicing Regulation under Genotoxic Stress Dawn Chandler
79John Kipp
Regulation of PD-L1 expression through antisense oligonucleotide treatment. Dawn Chandler
127Emeline Scott
Generation of pug1, pug1met2, met2 in C. albicans assessing pseudouridine degradation Doug Bernstein
56Humna Hasan
Understanding role of RNAs localized into extracellular vesicles and pathways of their selective export Dr. Andrea Kasinski
16Madhanagopal Barathraj
Switchback DNA: A double helix with a difference Dr. Arun Richard Chandrasekaran
148Rachel Trebesch
Role of RNA Structure in Gene Regulation by sRNAs Dr. Janie Frandsen
145Iranna Todkari
Resolving altered base-pairing of RNA modifications with DNA nanoswitches Dr. Ken Halvorsen
71Vikas Kaushik
mTORC2 phosphorylation induces configurational changes in IMP1 resulting in modulation of RNA recognition Edwin Antony
164Maria Zea
Crosstalk between DEAD box RNA helicase Dbp2 and RNA Pol II kinetics on transcription termination Elizabeth Tran
38Subhadeep Das
Unraveling the Role of DDX5 in Small Cell Lung Cancer Elizabeth Tran
110Katelynn Pranger
Synthesis of 2’F-Modified RNA Aptamers Emil Khisamutdinov
59Hannah Hayth
Bioconjugation of functionalized oligodeoxynucleotides to fluorescence reporters Emil Khisamutdinov
46Caleb Embree
Loss of Function of Activated Spliceosome Components Reduces Nonsense Mediated mRNA Decay Efficiency Guramrit Singh
2Rabab Abu Alhasan
Investigating the role of UPF3 factors in the rearrangement and function of premature translation termination complex Guramrit Singh
55Benjamin Hanson
Unraveling Cellular Consequences of SF3B1 mutations in Myelodysplastic Syndromes Hai Dang Nguyen
94Matthew McMahon
R-loop accumulation induced by RNA splicing perturbation triggers a discrete PARP2 response Hai Dang Nguyen
93Alexander Mckeeken
Title not published online Hai Dang Nguyen
31Victor Corral
Title not published online Hai Dang Nguyen
130Sajad Shiekh
Title not published online Hamza Balci
81Sineth G Kodikara
Detecting secondary structure formation with FRET-PAINT Hamza Balci
15Hamza Balci
Single Molecule Investigations of Telomere Accessibility and Protection by Shelterin Hamza Balci
36Ruwani Madushika Dalath
Imaging lncRNA TERRA with fluorescent γPNA probes Huaiying Zhang
39Saurja DasGupta
RNA assembly in an RNA World Jack Szostak
23Isobel Bowles
A tRNA Specific Function for tRNA Methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiae Jane Jackman
67Grace Johnecheck
Substrate Recognition by Two 3′ to 5′ RNA Polymerases in Dictyostelium discoideum Jane Jackman
45Catherine Edgington
Assessing tRNA substrate specificity of archaeal homologs of the conserved tRNA methyltransferase Trm10 Jane Jackman
91Nisha Makkar
Investigating biological significance of tRNA acetyltransferase Tan1, methyltransferase Trm1, and pseudouridine synthase Pus1 tRNA substrates in Saccharomyces cerevisiae Jane Jackman
8Madison Allegretti
Investigating molecular interactions with 3’-5’ RNA polymerases in Dictyostelium Discoideum discoideum Jane Jackman
65Brandon Iwaniec
Identifying substrates of the 3’-5’ reverse polymerase in Myxococcus xanthus Jane Jackman
149Madison Turley
Ribonucleoprotein Mutational Profiling of Telomerase RNA Jens Schmidt
51Madeline Glennon
Title not published online Jessica Brown
131Krishna Shivakumar
Locked Nucleic Acid Oligonucleotides Facilitate RNA•LNA-RNA Triple Helix Formation and Reduce MALAT1 Levels Jessica Brown
89Gowthami Mahendran
Title not published online Jessica Brown
146Melissa Tosiano
Edc3p is not required for P-Body condensation, heat tolerance, or hyphal phenotype in diverse Candida albicans strains Joel McManus
108Lydia Phillips
Modeling the Effect of Nucleotide Variations on Secondary and Tertiary Structures Joel McManus
43Jacob Devos
RNA-based iron sensing: The czcD riboswitch and associated protein in Listeria monocytogenes Joey Cotruvo
83Shardul Kulkarni
Characterizing the function of the human CCR4-NOT complex using rapid degron systems. Joseph Reese
7Oluwasegun Akinniyi
Unexpected cytoplasmic functions of the RNAPII degradation factor, Def1 Joseph Reese
139Megan Sullivan
Probing the impact of SARS-CoV-2 nucleocapsid protein phosphorylation on its aggregation and RNA chaperone activities Karin Musier-Forsyth
24Christina Budding
Site-specific identification and role of m6A RNA modification in HIV-1 genomic RNA 5'UTR Karin Musier-Forsyth
141Yu-Ci Syu
Identification of specific tRNA-Pro isodecoder used by HTLV-1 to prime reverse transcription and role of host factors in chaperoning primer annealing Karin Musier-Forsyth
17Dina Bayachou
Investigating the effect of phosphomimetic mutations of SARS-CoV-2 nucleocapsid protein on viral RNA binding Karin Musier-Forsyth
52Keerthi Gottipati
Structural Basis of Nuclear Export of HIV-1 RNA Mediated by the Rev Response Element Kay Choi
1Jibin Abraham Punnoose
Single-molecule quantification of individual base-stacking energies using a Centrifuge Force Microscope Ken Halvorsen
126Andrew Savidge
Clinical de novo Argonaute mutations change the trajectory of the miRNA guide and lead to the production of 10-18 nt RNAs Kotaro Nakanishi
165Huaqun Zhang
Kinetics analysis of cityRNA-loaded human Argonaute2 and Argonaute3 Kotaro Nakanishi
132GeunYoung Sim
Title not published online Kotaro Nakanishi
101Sarah Nock
Yeast engineered for enhanced identification of protein interaction networks using in vivo Proximity Labeling Kristian Baker
135Laura Snyder
RNA modifications impact the rate of RNA synthesis by the SARS-CoV-2 replication and transcription complex Kristin Koutmou
50Rachel Giles
Guanosine mRNA modifications impact translation speed Kristin Koutmou
133Kaley Simcox
Quantitative mapping of modified RNA nucleosides in tRNAs Kristin Koutmou
154Benjamin Warner
Role of an alternative 16S rRNA helix in biogenesis of the 30S subunit Kurt Fredrick
9Siddik Alom
Title not published online Kurt Fredrick
99Fawwaz Naeem
Analysis of programmed frameshifting during translation of prfB in Flavobacterium johnsoniae Kurt Fredrick
42Trupti Devale
Role of stress granules in dsDNA activated Stimulator of Interferon Genes (STING) signaling pathway Malathi Krishnamurthy
32Allan Victor Cortes
Title not published online Mallory Havens
123Ezra Samson
ATXN3 exon 10 skipping as a potential therapeutic for SCA3 Mallory Havens
13Ava Artz
Title not published online Mallory Havens
117Austin Rockaitis
Using an Electrochemical Deblocking Step in ASO Synthesis to Produce Quicker and Higher Yields of Oligonucleotides Mallory Havens
168Joseph Hazel
Regulation of tryptophan biosynthesis through the interaction of the trp¬ RNA-binding attenuation protein (TRAP) and its inhibitor Anti-TRAP Mark Foster
161Haoyun Yang
Nearest-neighbor cooperativity in the Bacillus ring-shaped trp RNA binding attenuation protein (TRAP) from protein engineering and cryo-EM Mark Foster
29Amelia Cochran
Investigation of Pus4 Substrate Selection Markos Koutmos
144Elizabeth Liz Tidwell
High throughput screening of small molecule binding partners for the FMN riboswitch by a multidisciplinary approach Markos Koutmos
63Keontre Hughes
Improved high-resolution optical fleezers methods for investigating human telomerase Matthew J. Comstock
128Kasun Senanayake
Step-By-Step Binding and Unwinding Of RNA By A Ded1p Triplet Revealed By Combined High-Resolution Tweezers And Fluorescence Measurements Matthew J. Comstock
138Mara Stout
The role of topoisomerases in circularized chromosome strains of Saccharomyces cerevisiae Melissa Mefford
54Brittany Hamilton
Stability of circularized chromosomes lacking telomeres in Saccharomyces cerevisiae Melissa Mefford
158Mark Wilson
Global gene expression analysis in circularized chromosome strains of Saccharomyces cerevisiae Melissa Mefford
33Natalie Creech
Determining the role of the tRNA methyltransferase Trm7:Trm734 in repression of TY1 elements in yeast Michael Guy
41Ashton Davey
Bioinformatics approach for the identification of a box C/D guide RNA responsible for the Nm39 modification of tRNA Michael Guy
155Julia Warrick
Interrogating the RNA topoisomerase activity of the mRNA-binding protein TOP3B Michael Kearse
122Paul Russell
Deciphering mechanisms of ribosome turnover during global inhibition of translation elongation in mammalian cells Michael Kearse
49Caleb Frye
Host MicroRNA Interactions with the SARS-CoV-2 Viral Genome 3'-Untranslated Region MihaelaRita Mihailescu
34Caylee Cunningham
Characterization of the s2m G15U mutation associated with the SARS-CoV-2 Delta variant MihaelaRita Mihailescu
69Manju Kasaju
The Effect of a G-Quadruplex Structure in the Oct4 3’-Untranslated Region (UTR) on its Binding Interactions with miR-145-5p MihaelaRita Mihailescu
104Leeann Parsi
Biophysical Characterization of a G-Quadruplex Structure in the Sox2 mRNA 3’ UTR: Implications for Cancer MihaelaRita Mihailescu
53Lydia Grimaldi
The interactions between hnRNP K mRNA and miR-1249-3P are mediated by a non-canonical G-quadruplex structure MihaelaRita Mihailescu
113Kylie Raasch
Large-scale synthesis of pseudouridine using an immobilized enzyme Mina Sumita
25Nicole Burbach
Synthesis of fluorescent C-nucleoside: 2-aminopyridine Mina Sumita
35Liuhan Dai
Ultrafast, high-accuracy disease biomarker detection through fluorogenic single molecule recognition Nils Walter
143Jingxuan Tang
Neurodegenerative VCP Mutant and Wild type Co-assembly and Stoichiometry Assessment by Single Molecule Assays Nils Walter
150Satenik Valesyan
Detection of m5C modification in E. coli tRNA sequences and the enzyme responsible for its synthesis Pat Limbach
57Mohammed Hassan
RNA nanoparticles for enhancement of ocular drug delivery Pat Limbach
115Sandeepani Ranaweera
Genome-wide effects of NusA and NusG on intrinsic termination in Escherichia coli Paul Babitzke
80Kobie Kirven
SPARCS: A Modular, Containerized, and Scalable Pipeline for Genome-Wide RiboSNitch Prediction Phil Bevilacqua
73Reuben Kern
Potential Functional Roles of Self-cleaving Ribozymes in Oryza sativa (Rice) Phil Bevilacqua
125Md Sharear Saon
Roles for Charged and Tautomeric Nucleobases in RNA Structure Phil Bevilacqua
48Emma Eubank
Title not published online Philip Smaldino
70Isaiah Kaufman
Translation efficiency and evolution of the Kozak consensus sequence: What can Ribo-seq teach us? Polly Hsu
30Zhengmin Cong
MANCR modulates breast cancer metastasis by influencing Net1a expression in cis Prasanth Kannanganattu
87Minxue Liu
Monoallelically-expressed Noncoding RNAs form nucleolar territories on NOR-containing chromosomes and regulate rRNA expression Prasanth Kannanganattu
19Shivang Bhaskar
Effect of nucleolar stress on the localization of SNUL-1 ncRNA Prasanth Kannanganattu
6Miriam Akhnoukh
Title not published online Prasanth Kannanganattu
78Woo Joong Kim
Characterizing the impact of bulge nucleotide mutation on htrA thermometer Rachel Mitton-Fry
137Eiman Stiffler
Exploring the versatility of the MTR1 ribozyme Rachel Mitton-Fry
61Audrey Hoelscher
The role of YHR020W 5’ UTR isoforms in stress tolerance Rachel Niederer
92Cesar Martinez
Precise mapping of translation initiation sites using the bacterial toxin RelE Rachel Niederer
18Dana Beseiso
Investigating functional Transcription Start Site (TSS) switching in breast cancer Rachel Niederer
20Danielle Bingman
Title not published online Ralf Bundschuh
98Jagannath Misra
Title not published online Ronald C. Wek
11Grace Arhin
Identification of compounds targeting NPSL2 - a regulatory element in the oncomiR-1 RNA: A combined STD-NMR and molecular modelling approach Sarah Keane
157Megan Westwood
Investigation of the structure of pre-miR-122 and the features that impact Dicer processing efficiency Sarah Keane
136Sahiti Somalraju
Identification of polyA tails in human cell lines using nanopore sequencing Sarath Chandra Janga
124Neel Sangani
Transcriptome wide high throughput mapping of protein RNA occupancy profiles using POP seq Sarath Chandra Janga
120Poonam Roshan
Modulating ribosomal subunit-association dynamics to stall cancer growth Sofia Origanti
88Riley Luebbers
Deregulation of eIF6 in high grade invasive cancers Sofia Origanti
10Mary Brintha Croos Anburaj
Impact of guanine oxidation on RNA structure and function Soumitra Basu
90Thulasi Mahendran
Selective mRNA oxidation of the electron transport chain complex subunits in human neuronal cells dysregulate energy production in Multiple Sclerosis Soumitra Basu
68Mohammad Lutful Kabir
Exploring the Interplay of G-Quadruplexes and CRISPR/dCas9 in Gene Expression Regulation Soumitra Basu
97Arya Menon
Title not published online Stephanie Moon
116Imalka W Rathnayaka-Mudiyanselage
Interplay between 5’ nucleotide modifications and BR-body formation in bacterial mRNA decay Stephanie Moon
60Noah Helton
Analysis of stress-induced gene regulation by stress granules Stephanie Moon
151Tommy Vo
Elongator complex regulates non-coding small interfering RNAs Tommy Vo
163Walter Zahurancik
The Arabidopsis tandem CCCH zinc-finger protein AtTZF1 enhances salt stress tolerance by targeting the autoinhibited Ca2+-ATPase 11 (ACA11) mRNA Venkat Gopalan
74Eshan Khan
Title not published online Wayne Miles
82Ganesh Koshre
Title not published online Wayne Miles
27Ronghao Chen
The RNA-binding protein, PUM1, directly binds to and promotes the protein levels of PD-L1 in cancer cells. Wayne Miles
75Misbah Khan
Post-Transcriptional Regulation of Nuclear Encoded Mitochondrial Genes by Pumilio Proteins. Wayne Miles
105Benjamin Pastore
Pre-piRNA trimming prevents piRNAs from being erroneously targeted by RNA dependent RNA polymerase Wen Tang
153Yi-Hui Wang
Identification and characterization of novel proteins in the biogenesis of C. elegans PIWI-interacting RNAs Wen Tang
111Ian Price
Title not published online Wen Tang
159Matthew Wirick
FOXO/daf-16 opposes the expression of the conserved let-7 microRNA to regulate epidermal seam cell multipotency in C. elegans Xantha Karp
152Han Wang
Title not published online Xiao Li
76Benjamin Killam
Title not published online Yury Polikanov
103Madhura Paranjpe
Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin Yury Polikanov
162Clifford Yerby
Simultaneous binding of aminoglycosides to the ribosome could rationalize the increased bactericidal activity Yury Polikanov
140Egor Syroegin
Nascent peptide mediated displacement of macrolides from translating ribosome Yury Polikanov
109Yury Polikanov
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion Yury Polikanov
166Shurong Zhou
Engineering ADAR1-targeting Cas13d mRNA and circular guide RNA to sensitize triple-negative breast cancer for immunotherapy Zhu Guizhi