Poster abstracts

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Number Presenter Title PI
1Chenyu Lin
PufA regulates R-loop formation, DNA damage repair and chemotherapy resistance Wayne Miles
2Emily Fairchild
Peptides to inhibit the T-Box Riboswitch Jennifer Hines
3Robert Wang
Robust discovery and quantification of transcript isoforms from error-prone long-read RNA sequencing data Yi Xing
4Kailey Worner
A congenital hydrocephalus causing mutation in Trim71 results in stem-cell and neural-differentiation defects through inhibiting Lsd1 mRNA translation Wenqian Hu
5Archie Bhullar
The dynamic, motile and deformative properties of RNA nanoparticles facilitate the third milestone of drug development Peixuan Guo
6Fiona Fitzgerald
The DEAD-box helicase Drs1 plays a role in compaction of 25S rRNA domain III during nucleolar stages of large subunit assembly John Woolford
7Alan Mlotkowski
Computationally determined pKa values of modified nucleobases: more than just a series of numbers Christine Chow
8Ian Hall
Investigating Natural Variation in SAM-I Riboswitch Structure and Function Sarah Keane
9Aparna Biswas
Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit Sofia Origanti
10Kaushik Saha
Pre-mRNA 3D structural scaffold as a contributor to the mammalian splicing code Gourisankar Ghosh
11Feng Jiang
Title not published online Peng Yao
12Ben Jepson
Analysis of tRNA methyltransferase homologs from zebrafish reveals similarities and differences to human Trm10 enzymes Jane Jackman
13GeunYoung Sim
Manganese-dependent microRNA trimming by 3′→5′ exonucleases generates 14-nucleotide or shorter tiny RNAs. Kotaro Nakanishi
14Sun Jeong Im
Role of Modified Nucleotides in Mediating Structure and Oxidative Damage of U2 snRNA Christine Chow
15Justin Davis
Telomerase RNA biogenesis requires direct interactions of a core group of nucleolar family proteins in the parasitic protist, Trypanosoma brucei Kausik Chakrabarti
16Yi Xing
isoCirc catalogs full-length circular RNA isoforms in human transcriptomes Yi Xing
17Ian Price
Title not published online Wen Tang
18Joseph Smith Jr.
Massive upregulation of COII mRNA editing correlates with alterations in RESC protein and RNA interactions during T. brucei differentiation Laurie Read
19Grace Johnecheck
Substrate recognition by two 3′ to 5′ RNA polymerases in Dictyostelium discoideum Jane Jackman
20Satenik Valesyan
LC-MS/MS-based detection of 5-methyl cytidine in E. coli tRNAs arising from oxidative stress Pat Limbach
21Madeline Glennon
Title not published online Jessica Brown
22Nishanti Sudhakar
RNA Tert-Seq - a biochemical pipeline to discover novel functional RNAs with tertiary structure Phil Bevilacqua
23Yi-Hui Wang
Investigating transcriptional program of C. elegans piRNA expression Wen Tang
24Reuben Kern
Quantifying cleavage of known and novel twister ribozymes in vivo in rice Phil Bevilacqua
25Anwesha Ghosh
Elucidating the role of RNA modifications in acetate-grown and methanol-grown Methanosarcina acetivorans Phil Bevilacqua
26Haiyun Liu
Nucleic Acid Protective and Rescuing Properties of Early Earth Coacervates Phil Bevilacqua
27Mika Schievelbein
Does the MALAT1 Triple Helix Form in the Presence of mascRNA? Jessica Brown
28Jahree Sosa
Functional implications of a cancer-associated mutation on LARP1 DM15 region Andrea Berman
29Caleb Embree
Disruption of spliceosomal proteins reduces NMD efficiency Guramrit Singh
30Erwin Doe
Bioconjugation of functionalized oligodeoxynucleotides to hydrophobic fluorescence reporters Emil Khisamutdinov
31Gowthami Mahendran
Title not published online Jessica Brown
32Tiffany Barwell
Dissecting cross-talks between intron turnover pathway and nonsense mediated decay via the interactions of RNA debranching enzyme, DBR1 Kausik Chakrabarti
33Hannah Hertz
Comparative analysis of piRNA sequences, targets and functions in nematodes Wen Tang
34Kobie Kirven
MLSnitch: Towards a Machine Learning Method for RiboSNitch Prediction Phil Bevilacqua
35Krishna Shivakumar
Title not published online Jessica Brown
36Cassandra Catacalos
Polyadenylation site choice correlates with epitranscriptomic mark, N6-methyladenosine (m6A), in Plasmodium falciparum Kausik Chakrabarti
37Qian He
The N-Terminal Domain of Eukaryotic Translation Initiation Factor 4B promotes P body Levels in Yeast Sarah Walker
38Aldrex Munsayac
Small-angle scattering techniques as a structural tool to study RNA:RNA complexes Sarah Keane
39Brandon Iwaniec
Determining the role of the 3’-5’ reverse polymerase in Myxococcus xanthus Jane Jackman
40Nicholas Arredondo
Trans-spliced Leader Sequences Present a Novel Evolutionary Target of the DM15 Region of LARP1
41Yaping Liu
Structural basis for terminal loop recognition and stimulation of miR-20a processing by hnRNPA1 and hnRNPA2B1 Sarah Keane
42Kaitlin Klotz
Structural and Functional Profiling of telomerase RNA domain deletion mutants in Trypanosoma brucei, a deep-branching parasitic agent of neuropathology in mammals Kausik Chakrabarti
43Sicong Ma
Regulatory structural features of pre-miR-31 for Dicer processing Sarah Keane
44Deepak Shrestha
Title not published online Christine Chow
45Mingyi Zhu
DecoyFinder: Identification of Decoy Sequences in Sets of Homologous RNA Sequences David Mathews
46Bayley Carter
Investigating PYM1 function in cellular and flaviviral gene expression
47Rhiannon McCracken
Structural and functional analysis of Crassostrea gigas OAZ-PK RNA Juliane Soukup
48Jose Reyes Franceschi
Development of a chemo-transcriptomic platform for identifying RNA-binding small molecules Amanda L. Garner
49Ashutosh Dubey
KREH1 RNA helicase activity promotes utilization of initiator gRNAs across multiple mRNAs in trypanosome RNA editing Laurie Read
50Anindhya Sundar Das
Aminoacyl-tRNA synthetase complex-interacting multifunctional protein 3 (AIMP3) is essential for physiological function of heart Federica Accornero
51Emil Khisamutdinov
Evaluation of isosteric substitutions of non-Watson-Crick basepairs in recurrent RNA 3D motifs Emil Khisamutdinov
52Andrew Weeks
Zinc-dependent regulation of sod1 mRNA transcript levels.
53Vasilios Orologas
Super resolution nanoscopy of Trypanosoma brucei RNA binding protein 42 during acute infection in mice Vivian Bellofatto
54Evan Spell
Characterization of pug1/gap2 double knockout in the human fungal pathogen C. albicans Doug Bernstein
55Jarrett Wilson
Recognition of RNA duplexes by the tRNAHis guanylyltransferase​ Jane Jackman
56Sarah Nock
Proximity labeling to investigate protein dynamics mediating nonsense-mediated mRNA decay in yeast Kristian Baker
57Phillip McCown
Improved long non-coding RNA annotation and detection in human transcriptomic profiles Matthias Kretzler
58Taylor Ayers
Differential m5C in embryonic mRNA reveals methyltransferase specificity
59Samuel Seibert
Investigating the formation and function of 2’-O-methylation in the anticodon loop of tRNAPhe Michael Guy
60Chase Morse
Spectra of ribonucleosides in hyperglycemic mammalian cells and diabetic murine cardiac models
61Kenzie Scarpitti
A non-canonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes Michael Kearse
62Daisy DiVita
New insights into the alternative translation initiation factor eIF2A Michael Kearse
63Minli Ruan
Determining the Influence of PUS7 localization on RNA Substrate Selection Kristin Koutmou
64Sara Ali
Mutate2test: New Algorithm and Software for Mutational Design David Mathews
65Justin Mabin
Knockout of three U5 snRNA sequence variants in 293T cells alters splicing and expression of an overlapping set of genes David Brow and Peter Lewis
66Rachel Giles
Inosine mRNA modifications impact translation elongation Kristin Koutmou
67Gabrielle Caito
Title not published online
68Tulsi Bhandari
Analysis of photo-oxidation induced products of post-transcriptional modifications in tRNA using LC-MS/MS technique Pat Limbach
69Sajad Shiekh
FRET-PAINT for Studying Long Telomeric DNA Overhangs and Their Interactions with Shelterin Proteins Hamza Balci
70Abdul McKinney
Title not published online Hua Lou
71Akila Venkataramany
Modulating insulin receptor alternative splicing for therapeutic benefit in Ewing sarcoma
72Madison Allegretti
Investigating molecular interactions with 3’-5’ RNA polymerases in Dictyostelium Discoideum
73Benjamin Warner
A crucial role for the leader-trailer helix and minor role for the antitermination complex in biogenesis of the 30S ribosomal subunit Kurt Fredrick
74Caleb Gooden
Characterization of alternative polyadenylation in roots of red clover Arthur Hunt
75Asif Rayhan
Title not published online Pat Limbach
76Sepideh Fakhretaha Aval
Role of the sarcin-ricin loop (SRL) of 23S rRNA in assembly of the 50S ribosomal subunit Kurt Fredrick
77Amelia Cochran
Biochemical and structural analysis of Pus4 mRNA target selection
78Yu-Ci Syu
Role of HTLV-1 Gag-host factor interactions in chaperoning tRNA-Pro primer annealing
79Kurtis Breger
Title not published online Jessica Brown
80Joe Kanlong
Title not published online
81Alezandra Hernandez
Plant-exclusive domain of trans-editing enzyme ProXp-ala confers dimerization and enhanced tRNA binding Karin Musier-Forsyth
82Ingrid Kilde
Exploring structural determinants of ligand selectivity in cobalamin riboswitches
83Shardul Kulkarni
Characterizing the function of the human CCR4-NOT complex using rapid degron systems. Joseph Reese
84Emily Erdmann
Investigating the Role of ADARs and A-to-I RNA editing in Germline RNA Regulation Heather Hundley
85Katie Clark
tRNA family-specific turnover pathways and environmental stresses regulate tRNA intron degradation
86Sandip Chorghade
Post-transcriptional silencing of the nuclear poly(A) binding protein N1 is critical for postnatal maturation and function of the heart Auinash Kalsotra
87Nicholas Baker
Temporally controlled expression of a splicing factor in single cells coordinates the metabolic and proliferative activities of regenerating livers
88Ullas Valiya Chembazhi
Transcriptional and post-transcriptional landscapes of alcohol-associated human liver diseases
89Subhashis Natua
Cardiomyocyte-specific knockout of nuclear poly(A)-binding protein leads to heart failure and death
90Anna Vradi
Discriminator Base is a Critical Recognition Element for Trypanosoma Brucei Ala-tRNAPro Editing Domains
91Gabriel Silveira dAlmeida
RRP44 contributes to the unusually short half-life of tRNATyr in T. brucei Juan Alfonzo
92Bohye Jeong
Translational regulation of photoreceptor-specific mRNA by Musashi 1 and Musashi 2 proteins for photoreceptor maintenance Peter Stoilov
93Ananya Mahapatra
Characterizing the Role of ADARs in Regulating Insulin Signaling and Inter-Organ Communication Heather Hundley
94Alfa Dhakal
Role of ADARs in the pathogen response of C. elegans Heather Hundley
95Lankani Gunaratne
Understanding the function of the La protein in Trypanosoma brucei
96Rylan Watkins
Investigating the Role of Trypanosoma brucei Prolyl-tRNA Synthetase and MCP3 in Maintaining tRNAPro Translational Fidelity Karin Musier-Forsyth
97Boyoon Yang
Gathering insights into the importance of ADR-1/ADR-2 interaction in RNA editing in vivo Heather Hundley
98Cailyn Leo
Characterization of novel TRMT1 variants linked to intellectual disability disorders in the human population Dragony Fu
99Priyanka Mukherjee
Long noncoding RNAs are abundant targets of ADAR3 in glioblastoma Heather Hundley
100Arden Bui
AtRTD2 versus AtRTD3: how Serine/Arginine-rich 45 affects the sperm transcriptome in Arabidopsis thaliana based on 2 versions of transcriptome reference Xiao-Ning Zhang
101Serena Fan
The Interplay within the ASAP Complex in Arabidopsis thaliana Xiao-Ning Zhang
102David Goich
Crosstalk and compensation between the Hog1 and Gcn2 pathways in C. neoformans stress adaptation. John Panepinto
103Sean Duffy
Upf1 is required for translational response to oxidative stress in Cryptococcus neoformans John Panepinto
104Siddik Alom
Ribosomal protein bL38 a uniquely conserved component of the Bacteroidia ribosome Kurt Fredrick
105Jillian Wagner
Title not published online
106Amanda Bloom
C. neoformans casein kinase Yck2 contributes to translational reprogramming and cell wall remodeling during temperature stress John Panepinto
107Zac LaRocca-Stravalle
The dichotomy of MDM2 splicing regulation in response to genotoxic stress
108John Kipp
Regulation of pd-l1 expression through splice-switching oligonucleotide treatment.
109Paul Russell
Small uORFs favor translation re-initiation but do not protect mRNAs from nonsense-mediated decay Michael Kearse
110Mohamed Rushdhi Mohamed Rauff
Title not published online Sanjaya Abeysirigunawardena
111Sudeshi Abedeera
Title not published online Sanjaya Abeysirigunawardena
112Thulasi Mahendran
Selective mRNA oxidation of the mitochondrial electron transport chain complex subunits in human neuronal cells dysregulate energy production in Multiple Sclerosis Soumitra Basu
113Jiale Xie
Title not published online Sanjaya Abeysirigunawardena
114Zezhong Wan
mRNA modifications impact stop codon recognition Kristin Koutmou
115Catherine Wilhelm
Structural and kinetic characterization of multiple oligomeric states in a minimal protein-only RNase P Markos Koutmos
116Erik Koppes
Ablation of the imprinted PWS-orthologous domain in a rat insulinoma cell line reveals cell-autonomous transcriptional deficiencies in peptide hormones and ER chaperones independent of ER stress Nicholls Robert D.
117Jae Lee
Investigating the relationship between structure and function of htrA RNA Thermometer
118Corey Knowles
Stress-induced translational control induces the ISR in the human pathogen Cryptococcus neoformans John Panepinto
119Fawwaz Naeem
Sequestration of the anti-Shine-Dalgarno (ASD) causes reduced efficiency of prfB programmed frameshifting in Flavobacterium johnsoniae
120Vaishnavi Sidharthan
Identification of inhibitors of Methanobrevibacter smithii RNase P using small molecule microarrays Venkat Gopalan
121Kaizheng Liu
Reversible Acylating Reagents to Dictate RNA’s Fate Anna M. Kietrys
122Alex Runyon
Understanding canonical T-box riboswitches: A study of the Bacillus subtilis thrS RNA Tina Henkin
123Melissa Tosiano
RNP granule condensation: a potential mechanism for post-transcriptional regulation of the yeast-to-hyphal transition in Candida albicans Joel McManus
124Chenghong Deng
The influence on transcription and translation by the TRMT1 tRNA modification enzyme Dragony Fu
125Katherine Tucker
PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing
126Mohammed Enamul Hoque
Transcription regulation by CRISPR/dCas9 complex in the context of G-quadruplex structure Soumitra Basu
127Vikas Kaushik
Deciphering the principles of RNA binding specificity of multi-domained proteins using non-canonical amino acids Edwin Antony
128Safiya Khurshid
Deciphering the function of MDM2-ALT1 splice isoform using a novel mouse model. Dawn Chandler
129Walter Zahurancik
Modulation of archaeal RNase P ribozyme activity by temperature- and metal-ion–dependent phase separation Venkat Gopalan
130Megan Van Horn
A method for isolation of target circular RNAs through specific biotinylated-DNA probes Anna M. Kietrys
131Ila Marathe
Establishing robust calibration curves for mass photometry-based measurements of RNAs and ribonucleoprotein complexes Vicki Wysocki
132Gable Wadsworth
Entropy-driven Phase Transition of RNA Priya Banerjee
133Evan Corden
Title not published online Joel McManus
134Mohammed Hassan
The use of RNA nanoparticles as vectors for ocular drug delivery Pat Limbach
135Jian Shi
Identification of Circular RNAs in Early Human Immunodeficiency Virus Infection Anna M. Kietrys
136Avleen Chawla
The catalytic activity of H1 circRNA Anna M. Kietrys
137Raahul Sriram
Title not published online
138Mary brintha croos Anburaj
Stability and functional effect of RNA G-quadruplex within the open reading frame of NAT8L mRNA under oxidative stress Soumitra Basu
139Bereketab Abeje
Title not published online
140Anees Mohammed Keedakkatt Puthenpeedikak
Refinement of the Amber Force Field For RNA: Improving the Description of Non-Bonded Interactions David Mathews
141Evan Rogers
Role of Dhx36/G4R1 in coronary angiogenesis and heart development Philip Smaldino
142Sushant Bangru
Title not published online Auinash Kalsotra
143Samantha Gargasz
Regulation of the Oncogenic Androgen Receptor Variant 7 by micro and long noncoding RNAs in Prostate Cancer Girish Shukla
144Surbhi Sona
Single-Cell and Spatial Mapping Identify Cell Types and Signaling Networks in the Human Ureter with Regards to its Regenerative Potential
145Ying Xu
Title not published online Fu-Sen Liang
146Elizabeth Liz Tidwell
High throughput screening of small molecule binding partners for the FMN riboswitch by a multidisciplinary approach Markos Koutmos
147Haoyun Yang
Dynamics of RNA Conformational Sampling by the SMK box riboswitch Mark Foster
148Christina Haddad
Title not published online Blanton Tolbert
149Scott Abernathy
Investigating the effectiveness of HILIC-type column chemistries for oligonucleotides Pat Limbach
150Jeff Levengood
Utilization of high-pressure NMR for the study of allosteric regulation of hnRNP A1 Blanton Tolbert
151Melanie Clawson
Semi-enzymatic Synthesis of Pseudouridine
152Nicole Burbach
Purification with
153Anthony Degregorio
Synthesis of 1-Aminopyridine for Fluorescent Studies of RNA
154Anita Dhara
The role of pumilio homolog 1 (PUM1) in human hemoglobin switching and erythroid differentiation Nithya Merlin Gnanapragasam
155Christina Rabeler
Ectopic expression of HSATII RNA results in nuclear focal accumulations and chromatin defects
156Bappaditya Roy
Ribosomes lacking bS21 gain function to regulate protein synthesis Kurt Fredrick
157Sk Abdus Sayeed
Investigating TERRA functions in VSG switching and telomere maintenance in Trypanosoma brucei Bibo Li
158Christina Akirtava
Unraveling the roles of 5’ transcript leaders in gene regulation
159Aubree Zimmer
The basis of multi-step tRNA recognition by a eukaryotic tRNA editing deaminase Juan Alfonzo
160Sineth G Kodikara
Single-Molecule Study of Telomeric Overhangs Using FRET Method Hamza Balci