Poster abstracts

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Number Presenter Title PI
1Fuad Abbas
Developing an optimal AID-degron system to elucidate UPF protein function in human cells Guramrit Singh
2Sudeshi Madushani Abedeera
Title not published online Sanjaya Abeysirigunawardena
3Christina Akirtava
Quantitative analysis of yeast Kozak variants for AUG and near-AUG start codons using a massively parallel reporter assay Joel McManus
4Ali Aldhumani
RNA drug discovery: developing computational models to predict ‘hit’ compounds Jennifer Hines
5Rolando Alvarado
Cytoplasmic recapping, a new epitranscriptomic modification targeting long non-coding RNA Daniel Kiss
6James Aretakis
Exploring the global determinants of bacterial mRNA decay Jared Schrader
7Jowad Atway
Understanding the Novel Cleavage behavior of RNase Cusativin through Site-Specific Mutagenesis and Liquid Chromatography coupled with Mass Spectrometry Balasubrahmanyam Addepalli
8Lauren Aufdembrink
RAQ-NASBA: Rapid, Aptamer-detected, Quantitative Nucleic Acid Sequence Based Amplification Aaron Engelhart
9Armend Axhemi
Functional synergy between Rrp6p and Rrp44p in the nuclear exosome Eckhard Jankowsky
10Jared Baisden
A transient RNA protonation state modulates oncogenic microRNA-21 maturation Qi Zhang
11Sushant Bangru
Temporal control of ESRP2 licenses fetal-to-adult switch in alternative splicing required for hepatocyte maturation Auinash Kalsotra
12Katherine Berman
Cotranscriptional RNA strand invasion mediates ligand sensing in the E. coli thiB thiamine pyrophosphate riboswitch Julius Lucks
13Divyaa Bhagdikar
Comparative analysis of translational and transcriptional S-box riboswitches Tina Henkin
14Mohammed Husain Bharmal
Probing determinants of translation initiation in non-SD mRNAs Jared Schrader
15Asmita Bhattarai
Hsa-miR-149 Mediated Posttransriptional Control of Steroid Biosynthesis Pathway in Prostate Cancer Girish Shukla
16Anton Blatnik
Identification of Functional SMNs and Suppressors of the Nonfunctional SMNE134K Arthur H M Burghes
17Kathryn Bormes
Role of Upstream RNA Secondary Structures in an RNA Thermometer from Bradyrhizobium japonicum Phil Bevilacqua
18Elaina Boyle
Title not published online Karin Musier-Forsyth
19Rachel Braun
Assessing the utility of a novel fluorescence turn-on assay for RNase P Venkat Gopalan
20Kurtis Breger
Elucidating the Kinetic Mechanism of Human METTL16 Jessica Brown
21Audrey Bui
Title not published online Xiao-Ning Zhang
22Jun-Kyu Byun
Role of Unique C-terminal Domain in a Plant Aminoacyl-tRNA Trans-editing Protein Karin Musier-Forsyth
23Menglin Chen
Measures of single- versus multiple-round translation argue against a mechanism to ensure coupling of transcription and translation Kurt Fredrick
24Luyi Cheng
A mechanistic study of the pbuE adenine riboswitch from the perspective of cotranscriptional chemical probing Julius Lucks
25Matthew Russon
Characterizing the Role of the DEAD-Box RNA helicase DDX5 in Small Cell Lung Cancer Elizabeth Tran
26Sara Cloutier
Genome-wide analysis of R-loops and nascent transcript synthesis in S. cerevisiae Elizabeth Tran
27Adriana Coke
Role of Exonucleases in RNA Polymerase V Transcript Degradation Wierzbicki Andrzej
28Kyle Crocker
A quantitative model of temperature actuated DNA origami nanocaliper constructs Ralf Bundschuh
29Noah Daniels
Investigating the Role of DDX41 in pre-messenger RNA Splicing and Leukemogenesis Richard Padgett
30Indrajit Deb
Insights into RNA recognition of small molecules using the Fragment Molecular Orbital (FMO) method Frank Aaron
31Amanda DiLoreto
Kinetic Analysis of ATP Dissociation from wt-Rok1p and its truncated variants Ivelitza Garcia
32Samantha Dodbele
Investigation into the function and mechanism of an orphan 3’-5’ polymerase implicated in noncoding RNA processing. Jane Jackman
33Catherine Douds
In vivo RNA structure prediction by motif constraining: an integrative approach Catherine Douds
34Lili Du
Arrowtail RNA for Ligand Display on Ginger derived Exosome-like Nanovesicles to deliver siRNA for Cancer Suppression Peixuan Guo
35Ashutosh Dubey
The RESC protein, MRB800 plays an important role in RNA editing progression by stabilizing protein-RNA and protein-protein interactions in Trypanosoma brucei Laurie Read
36Glenn Duncan
Title not published online Phil Bevilacqua
37Molly Evans
Maximizing quantitative structural information from high-throughput RNA structure probing Julius Lucks
38Jordan Farr
Pathogenic CLP1 p.R140H mutation alters mRNA processing in human motor neurons Ashleigh Schaffer
39Fiona Fitzgerald
Investigating the role of the DEAD-box helicase Drs1 in assembly of pre-60S subunits in Saccharomyces cerevisiae John Woolford
40Monika Franco
Pseudouridinylation of mRNA coding sequences alters translation Kristin Koutmou
41Gayathri Panangipalli
Maternal THC exposure leads to large-scale downregulation of genes in pre-frontal cortex of developing mouse brain Sarath Janga
42Varun Gadkari
Characterizing FMN-analogs binding the FMN riboswitch by native ion mobility-mass spectrometry Ruotolo Brandon
43Tyler Galbraith
Lethal Mutation in 16S rRNA cause defects in RNA Chaperone Activity of RsmC Sanjaya Abeysirigunawardena
44Zac Dewald
The role of Myotonic Dystrophy Type 1 in the Liver Auinash Kalsotra
45Keshav Gc
Moonlighting of RsmC as RNA chaperone and annealer protein Sanjaya Abeysirigunawardena
46Prabar Ghosh
3′UTR-mediated localization of mRNAs to the rear of migrating aortic endothelial cells Paul Fox
47Michelle Gibbs
Functional analysis of BipA in E. coli reveals the plasticity of 50S ribosome assembly Kurt Fredrick
48Prabesh Gyawali
A Single Molecule Study of the Impact of Small Molecules on Intermolecular G-Quadruplex Formation Hamza Balci
49Ian Hall
Interactions of structured regulatory RNAs Sarah Keane
50Sherrell Haney
Improving cell permeability of a ribosome targeting peptide as a potential antibiotic Christine Chow
51Jordan Hartung
Toehold Mediated Shape Transition of Nucleic Acid Nanoparticles Emil Khisamutdinov
52Joseph Heili
Activation of caged functional RNAs by oxidative desulfurization of 2-thiouridine Aaron Engelhart
53Courtney Hershberger
Complex landscape of splicing signatures in myeloid neoplasms Richard Padgett
54Tanner Hoog
Nucleolin Potentially Regulates G4-Duplex Equilibration During Ribosome Maturation Through Chaotropic Residues Aaron Engelhart
55Mohammed Enamul Hoque
piRNA mediated dual gene knockdown via the ping-pong mechanism Soumitra Basu
56Md Ismail Hossain
Modulation of T-box riboswitch function by analogs of 4,5-disubstituted oxazolidinones Jennifer Hines
57Ruochuan Huang
Effects of cellular concentrations of nucleotide diphosphate-chelated Mg2+ on RNA and DNA enzymes Phil Bevilacqua
58Kumudie Jayalath
Pseudouridylation enzyme RsuA binding and its activity is modulated by ribosomal proteins and local rRNA structures Sanjaya Abeysirigunawardena
59Malithi Jayasinghe
Reverse (3'-5') RNA polymerases: Applications beyond tRNAHis maturation and non-coding RNA processing Jane Jackman
60Ben Jepson
Understanding the biological significance of multiple zebrafish Trm10 homologs Jane Jackman
61Evan Jones
Theoretical pKa determinations of modified nucleobases using an implicit-explicit solvation model Christine Chow
62Joshua Jones
Title not published online Kristin Koutmou
63Manasses Jora
Pushing the boundaries of ribonucleoside detection and discovery by liquid chromatography-tandem mass spectrometry (LC-MS/MS) Pat Limbach
64Murat C. Kalem
Post-transcriptional regulation of caspofungin resistance in Cryptococcus neoformans. John Panepinto
65Michael Kearse
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors Michael Kearse
66Krishnendu Khan
Title not published online Paul Fox
67Kunal Khanna
A novel single molecule microscopy technique for extremely specific sensing of microRNAs with greater sensitivity Nils Walter
68Safiya Khurshid
Modulation of insulin receptor alternative splicing to develop cancer therapeutics Dawn Chandler
69Alexander Krohannon
CASowary: a tool for systematic design and optimization of cas13 guide RNAs to facilitate disrupting mRNA function Sarath Janga
70Jan Kucinski
RNase H1 is required for Arabidopsis thaliana embryonic development Wierzbicki Andrzej
71Charlotte Kunkler
Stability of RNA•DNA-DNA triple helices depends on base triple composition and length of the RNA strand Jessica Brown
72Stella Lai
A Tale of Two Types of Archaeal RNase P: Of Rate-Limiting Steps and Subunit Stoichiometries Venkat Gopalan
73Richard A. Lease
Stem-loop Antisense RNA and DNA Exclude Mismatched Target Sequences Richard Lease
74Kuan-Chieh Leu
CstF complex regulates an unique polyadenylation machinery in Arabidopsis thaliana Arthur Hunt
75Jeff Levengood
Strategies for utilizing NMR to gain insights into an intrinsically disordered domain of hnRNP A1 Blanton Tolbert
76Yufeng Liang
Conformationally-sensitive cleavage of human telomere DNA via molecular recognition of the loop region Dennis Bong
77Katie Lichtenthal
Determining the mechanism of cooperative binding of trp to TRAP using Bacillus halodurans Paul Gollnick
78Eviania Likos
Androgen Receptor messenger RNA Metabolism Girish Shukla
79Yichen Liu
Title not published online Aaron Frank
80Levan Lomidze
Stability factors of monomolecular DNA and RNA quadruplexes Karin Musier-Forsyth
81Justin Mabin
Diversity and plasticity of human spliceosomal small nuclear RNA variants Heidi Dvinge
82Monica Mannings
Pnrc2 promotes 3'UTR-dependent oscillatory transcript decay during vertebrate segmentation Sharon Amacher
83Ila Marathe
Use of FRET and SHAPE-Seq to elucidate structure-function relationships in archaeal RNase P, a multi-subunit catalytic ribonucleoprotein Venkat Gopalan
84Fatimah Matalkah
A glance at the role of KHDRBS3 in the tumorigenesis of TNBC Peter Stoilov
85Claire Mazahery
Opioid-induced long noncoding transcriptome of human CD8+ T cells reveals opioid receptor subclass specific responses Alan Levine
86Phillip McCown
Title not published online Jessica Brown
87Zakkary McNutt
Investigating the role of the Anti-Shine Dalgarno in the Bacteroidetes Kurt Fredrick
88McCauley Meyer
Nucleotide level resolution of RNA folding interactions within peptide-based complex coacervates Phil Bevilacqua
89Shiqin Miao
Duplex Stem Replacement with bPNA+ Triplex Hybrid Stems Enables Reporting on Tertiary Interactions of Internal RNA Domains Dennis Bong
90Luke Miller
Development of novel tools to characterize mRNA chemical modifications Kristin Koutmou
91Savannah Mills
Contribution of mRNA 3’ UTRs in substrate recognition by the nonsense-mediated mRNA decay pathway Kristian Baker
92Quoseena Mir
Identification of splice isoforms in T helper (Th) cells using Nanopore-based cDNA sequencing Sarath Janga
93Youssef Hegazy
Characterization of R-loop structures in budding yeast Elizabeth Tran
94Amartya Mishra
Modulation of RNA Editing Helicase 1 level regulates RNA editing profile of mitochondrial transcripts in trypanosomes Laurie Read
95Chaitali Misra
Overexpression of a non-muscle RBFOX2 splice isoform induce cardiac arrhythmias in Myotonic Dystrophy Auinash Kalsotra
96Alan Mlotkowski
Theoretical pKa calculations of modified purine nucleobases using explicit waters and a polarizable Ccontinuum model Christine Chow
97Mohamed Rushdhi Mohamed Rauff
Title not published online Sanjaya Abeysirigunawardena
98Jeremy Monroe
Translation is altered by the presence of N1-methylpseudouridine and 7-methylguanosine in mRNA coding regions Kristin Koutmou
99Rachel Morgeson
Identification of the methyltransferase responsible for 2’-O-methylation of tRNA residue 39 in plants Michael Guy
100Matthew Mouck
Computational Discovery of Riboswitches in the Human Microbiom Phil Bevilacqua
101Priyanka Mukherjee
Why do Glioblastomas require the non-functional deaminase ADAR3? Heather Hundley
102Golam Mustafa
Short looped DNA as a Force Transducer: Conversion of single molecule FRET signal into force information Hamza Balci
103Vishal Nanavaty
DNA methylation regulates alternative polyadenylation via CTCF and the cohesin complex Angela Ting
104Gina Nostramo
Do tRNA introns have a biological function? Anita Hopper
105V. Miguel Palomar
Structural features of plastid chromatin Andrzej Wierzbicki
106Rahi Patel
Title not published online Wayne Miles
107Chathuri Pathirage
Investigating the effect of post translational modifications of LysRS on HIV-1 gRNA binding Karin Musier-Forsyth
108Robert Patton
Chemical crosslinking enhances RNA immunoprecipitation for efficient identification of binding sites of proteins that photo-crosslink poorly with RNA Ralf Bundschuh
109Matthew Pawlak
Perchlorate brine abrogates protein function whereas ribozymes thrive Aaron Engelhart
110Katelyn Perroz
Limited proteolysis of a DEAD-Box protein reveals small conformational changes Ivelitza Garcia
111Anu Puppala
Determinantion of recognition elements governing binding of human selenocysteine synthase (SepSecS) to its substrate tRNA Miljan Simonovic
112Reshma Raghava Kurup
Gene regulatory role of ADAR3 in Glioblastoma Heather Hundley
113Hamza Rahman
Purification and analysis of proteins associated with nonsense codon-containing mRNA in Saccharomyces cerevisiae Kristian Baker
114Swetha Rajasekaran
Pumilio-mediated post-transcriptional regulation of Dicer1 Wayne Miles
115Suba Rajendren
Molecular Mechanisms to Regulate RNA Editing in nervous system Heather Hundley
116Chad Ratterman
Branchpoint identity and branch length effects on lariat debranching enzyme activity Subha R. Das
117Michelle Raymond
Structural characterization of DEAD-Box protein peripheral domains Ivelitza Garcia
118Tristan Sanford
Optimization and Quantification of Biofilm Produced by Escherichia coli K12 for Selection of DNA Aptamers Mina Sumita
119Tracy Roach
Title not published online Jane Jackman
120Hafiz Rothi
Noncoding RNA-mediated DNA methylation controls nucleosome positioning Andrzej Wierzbick
121Bappaditya Roy
Global analysis of protein synthesis in Flavobacterium johnsoniae reveals the use of Kozak-like sequences in diverse bacteria Kurt Fredrick
122Sarah Rundell
Structure of bPNA triplex hybrid determined by x-ray crystallography Dennis Bong
123Alex Runyon
Importance of conserved elements in the Bacillus subtilis thrS T-box riboswitch Tina Henkin
124Arpita Saha
Functions of telomerase RNA (TR) core domains in its biogenesis and telomere maintenance in a medically relevant parasite, Trypanosoma brucei Bibo Li
125Ansuman Sahoo
Dynamic phosphorylation of yeast eIF4A drives changes in gene expression that couple protein synthesis with cell division Sarah Walker
126Manu Sanjeev
Role of SR proteins in mRNP packaging and Nonsense Mediated Decay Guramrit Singh
127Jens Schmidt
Mechanism of processive telomerase catalysis revealed by high-resolution optical tweezers Jens Schimidt
128Stefani Schmocker
Title not published online Sanjaya Abeysirigunawardena
129Nick Sebree
Identification of plant TRMT1 genes using fluorescent primer extension in yeast Michael Guy
130Elan Shatoff
Title not published online Ralf Bundschuh
131Jacob Sieg
LC-MS identification of riboswitch ligands Phil Bevilacqua
132Gabriel Silveira dAlmeida
Overcoming a “molecular ruler” mechanism: the unusual heterotrimeric tRNA splicing endonuclease of Trypanosoma brucei Juan Alfonzo
133Jagjit Singh
Modeling microcephaly in patient iPS cell-derived brain organoids with U4atac snRNA mutations Richard Padgett
134Tyler Smith
Mechanistic framework for understanding ribosome sliding on homopolymeric A stretches Markos Koutmos
135Joseph Smith Jr.
Two distinct mechanisms of CYb and COIII mRNA editing regulation in Trypanosoma brucei Laurie Read
136Sarah Spigelmyer
Identification of the enzyme responsible for the acp3U modification in bacteria Michael Guy
137Sukanya Srinivasan
Auxiliary domains of the mammalian DEAH/RHA helicase DHX36 work in concert with the helicase core domains to remodel RNA structures. Eckhard Jankowsky
138Mansi Srivastava
Transcriptome-wide high-throughput mapping of protein-RNA occupancy profiles using an integrated phase separation and crosslinking approach Sarath Janga
139Rajneesh Srivastava
Functional annotation of the human protein-RNA interaction network via transcriptome-wide pooled CRISPR/Cas9 screens to edit the RBP binding sites Sarath Janga
140Eric Strobel
A ligand gated strand displacement mechanism for ZTP riboswitch transcription control Julius Lucks
141Halle Stump
Exploring the role of adr-2 in the innate immune response of C. elegans Heather Hundley
142Andrew Sugarman
Structural Dynamics of HIV ESS2p RNA Element Blanton Tolbert
143Kathryn Sutter
Comparative Analysis of ATP Dissociation from Rok1p Variants of in the presence of RNA Ivelitza Garcia
144Matthew Tanner
mRNA splicing is a marker of molecular pathology and response to therapeutics in myotonic muscular dystrophy patients and mouse models Charles Thornton
145Trinh T Tat
High-resolution integrative analysis to define putative cytoplasmic RNA recapping sites in mammalian cells Daniel L. Kiss
146Minhchau To
S4-like domain regulates binding of RsuA to 16S rRNA Sanjaya Abeysirigunawardena
147Elizabeth Traverse
Stem-loop antisense RNA and DNA exclude mismatched target sequences Richard Lease
148Ullas Valiya Chembazhi
Single-cell transcriptomics reveal distinct fetal like cellular states during murine liver regeneration Auinash Kalsotra
149Megan Van Horn
Towards understanding the role of circRNAs in intracellular signaling pathways Anna M. Kietrys
150Sarah Venus
Interactions with Vaccinia Virus K7 Protein Alter the Biochemical Activity of the DEAD-Box RNA Helicase DDX3X Eckhard Jankowsky
151Hongzhi Wang
Title not published online Peixuan Guo
152Melissa Ward
Nuclear speckle protein SON's role in transcription regulation at an inducible reporter gene array Paula Bubulya
153Rebecca Wegman
Dissecting the role of protein arginine methylation on translation initiation factor eIF1A Michael Yu
154Robb Welty
RNA structure and dynamics act as a gate keeper of 3’ alternative splicing Nils Walter
155Daniel Wilson
Maintenance of the polypeptide exit tunnel marks a nucleoplasmic checkpoint in large ribosomal subunit assembly John Woolford
156Ashlynn Winkler
Synthesis of a fluorescent cytidine analogue Mina Sumita
157Ciara Witt
Using deep learning networks to solve the RNA design problem Frank Aaron
158Austin Woodard
SPR-SELEX: New Method to Determine DNA Aptamers that Targets E. coli for Biosensor Mina Sumita
159Jiangbin Wu
EPRS Is a Critical Translational Control Factor in Cardiac Fibrosis Peng Yao
160Congcong Xu
Title not published online Peixuan Guo
161Ziqiao Xu
De Novo Nucleic Acid Design Using Variational Autoencoder Aaron Frank
162Mengkun Yang
Tetrahelical monomolecular architecture of nucleic acids probed by NMR Karin Musier-Forsyth
163Adam Litterst
Creating Super-Aptamers with Modified Nucleobases for Biosensor Mina Sumita
164Angela Yu
Title not published online Julius Lucks
165Walter Zahurancik
Use of single-molecule fluorescence co-localization spectroscopy to study archaeal RNase P assembly Venkat Gopalan
166Huaqun Zhang
Folding Mechanism of An RNA Thermosensor from Listeria Monocytogenes Sarah Keane
167Kejia Zhang
Deciphering the biological function of tRNA methyltransferase 1 (TRMT1) using mouse models Dragony Fu
168Long Zhang
Title not published online Peixuan Guo
169Ruoxia Zhao
Deinococcus radiodurans Transfer RNA Modified Nucleosides are Minimally Impacted UV Radiation Pat Limbach
170Lixia Zhou
Title not published online Peixuan Guo
171Oliver Munyaradzi
Helical bPNA targeting U-rich RNA Dennis Bong
172Taylor Dodson
Quantitative analysis of post-transcriptional modifications from bacterial systems Erin Prestwich
173Bo Zhang
Identification of the mechanism for PABPN1 translational repression during cardiac development and hypertrophy Auinash Kalsotra